Steady-state vitamin [K.sub.2] plasma concentrations after intake of dairy products and soft gel capsules

SUBJECTS/METHODS: For 42 days, healthy men and postmenopausal women between 45 and 65 years of age daily consumed either yogurt K, yogurt Kplus or capsules. Circulating MK-7, 25-hydroxy vitamin D (25(OH)D) and markers for vitamin K status (uncarboxylated osteocalcin (ucOC) and desphospho-uncarboxyla...

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Veröffentlicht in:European journal of clinical nutrition 2016-07, Vol.70 (7), p.831
Hauptverfasser: Knapen, M.H.J, Braam, L.A.J.L.M, Teunissen, K.J, Hoofd, C.M. van't, Zwijsen, R.M.L, van den Heuvel, E.G.H.M, Vermeer, C
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Sprache:eng
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Zusammenfassung:SUBJECTS/METHODS: For 42 days, healthy men and postmenopausal women between 45 and 65 years of age daily consumed either yogurt K, yogurt Kplus or capsules. Circulating MK-7, 25-hydroxy vitamin D (25(OH)D) and markers for vitamin K status (uncarboxylated osteocalcin (ucOC) and desphospho-uncarboxylated matrix Gla-protein (dp-ucMGP)) were assessed. Plasma MK-7 was also measured during the washout period of 2 weeks. MK-7 and dp-ucMGP were measured in citrated plasma, and 25(OH)[D.sub.3] and ucOC were measured in the serum. European Journal of Clinical Nutrition (2016) 70, 831-836; doi: 10.1038/ejcn.2016.3; published online 24 February 2016
ISSN:0954-3007
DOI:10.1038/ejcn.2016.3