Notch Stimulates Both Self-Renewal and Lineage Plasticity in a Subset of Murine CD9.sup.High Committed Megakaryocytic Progenitors

This study aimed at reinvestigating the controversial contribution of Notch signaling to megakaryocytic lineage development. For that purpose, we combined colony assays and single cells progeny analyses of purified megakaryocyte-erythroid progenitors (MEP) after short-term cultures on recombinant No...

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Veröffentlicht in:PloS one 2016-04, Vol.11 (4)
Hauptverfasser: Weiss-Gayet, Michèle, Starck, Joëlle, Chaabouni, Azza, Chazaud, Bénédicte, Morlé, François
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Sprache:eng
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