PDGFR[beta] Is a Novel Marker of Stromal Activation in Oral Squamous Cell Carcinomas

Carcinoma associated fibroblasts (CAFs) form the main constituents of tumor stroma and play an important role in tumor growth and invasion. The presence of CAFs is a strong predictor of poor prognosis of head and neck squamous cell carcinoma. Despite significant progress in determining the role of C...

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Veröffentlicht in:	PloS one 2016-04, Vol.11 (4), p.e0154645
Hauptverfasser:	Kartha, Vinay K, Stawski, Lukasz, Han, Rong, Haines, Paul, Gallagher, George, Noonan, Vikki, Kukuruzinska, Maria, Monti, Stefano, Trojanowska, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Diagnosis Fibroblasts Physiological aspects Prognosis Risk factors Squamous cell carcinoma Tumor antigens
Online-Zugang:	Volltext
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