Construction and Experimental Validation of a Petri Net Model of Wnt/[beta]-Catenin Signaling

The Wnt/[beta]-catenin signaling pathway is important for multiple developmental processes and tissue maintenance in adults. Consequently, deregulated signaling is involved in a range of human diseases including cancer and developmental defects. A better understanding of the intricate regulatory mec...

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Veröffentlicht in:	PloS one 2016-05, Vol.11 (5)
Hauptverfasser:	Jacobsen, Annika, Heijmans, Nika, Verkaar, Folkert, Smit, Martine J, Heringa, Jaap, van Amerongen, Renée, Feenstra, K. Anton
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular signal transduction Genetic aspects Physiological aspects Wnt proteins
Online-Zugang:	Volltext
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