1,25.sub.2D.sub.3 Deficiency Induces Colon Inflammation via Secretion of Senescence-Associated Inflammatory Cytokines

Epidemiological studies showed that 1,25-Dihydroxyvitamin D[1,25(OH).sub.2 D.sub.3 ] insufficiency appears to be associated with aging and colon cancer while underlying biological mechanisms remain largely unknown. Inflammatory bowel disease is one of the risk factors for colon cancer. In this study...

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Veröffentlicht in:PloS one 2016-01, Vol.11 (1)
Hauptverfasser: Liu, Yun, Chen, Lulu, Zhi, Chunchun, Shen, Ming, Sun, Weiwei, Miao, Dengshun, Yuan, Xiaoqin
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Sprache:eng
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