Lack of Cytosolic Carboxypeptidase 1 Leads to Subfertility due to the Reduced Number of Antral Follicles in pcd.sup.3J-/- Females

Females homozygous for the Purkinje cell degeneration mutation (pcd) are fertile, although the success rate is much lower than in the wild type. We performed detailed analysis of reproductive abnormalities of pcd females. The number of oocytes produced following exogenous gonadotropin treatment was...

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Veröffentlicht in:	PloS one 2015-10, Vol.10 (10)
Hauptverfasser:	Song, Ning, Kim, Nameun, Xiao, Rui, Choi, Hojun, Chun, Hyo-Im, Kang, Min-Hee, Kim, Jin-Hoi, Seo, Kunho, Soundrarajan, Nagasundarapandian, Do, Jeong-Tae, Song, Hyuk, Ge, Zhao-Jia, Park, Chankyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Demographic aspects Female infertility Gene mutation Genetic aspects Risk factors
Online-Zugang:	Volltext
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