Specific Depletion of Ly6C.sup.hi Inflammatory Monocytes Prevents Immunopathology in Experimental Cerebral Malaria

Plasmodium berghei ANKA (PbA) infection of C57BL/6 mice leads to experimental cerebral malaria (ECM) that is commonly associated with serious T cell mediated damage. In other parasitic infection models, inflammatory monocytes have been shown to regulate Th1 responses but their role in ECM remains po...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	PloS one 2015-04, Vol.10 (4)
Hauptverfasser:	Schumak, Beatrix, Klocke, Katrin, Kuepper, Janina M, Biswas, Aindrila, Djie-Maletz, Andrea, Limmer, Andreas, van Rooijen, Nico, Mack, Matthias, Hoerauf, Achim, Dunay, Ildiko Rita
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Genetic engineering Health aspects House mouse Infection Malaria Monoclonal antibodies T cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!