Pharmacokinetic Studies of the Innovative Antituberculosis Drug Thiozonide in Plasma

We present here our results from studies of the pharmacokinetic parameters of the original antituberculosis agent thiozonide, 100-mg capsules (ZAO Farm-Sintez, Moscow) using single increasing doses in different groups of healthy volunteers in a phase I clinical trial.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutical chemistry journal 2015-06, Vol.49 (3), p.147-150
Hauptverfasser: Savchenko, A. Yu, Men’shikova, L. A., Ramenskaya, G. V., Smolyarchuk, E. A.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 150
container_issue 3
container_start_page 147
container_title Pharmaceutical chemistry journal
container_volume 49
creator Savchenko, A. Yu
Men’shikova, L. A.
Ramenskaya, G. V.
Smolyarchuk, E. A.
description We present here our results from studies of the pharmacokinetic parameters of the original antituberculosis agent thiozonide, 100-mg capsules (ZAO Farm-Sintez, Moscow) using single increasing doses in different groups of healthy volunteers in a phase I clinical trial.
doi_str_mv 10.1007/s11094-015-1243-7
format Article
fullrecord <record><control><sourceid>gale_cross</sourceid><recordid>TN_cdi_gale_infotracmisc_A424146604</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A424146604</galeid><sourcerecordid>A424146604</sourcerecordid><originalsourceid>FETCH-LOGICAL-c377t-4802983129362d4a2a8250ae17fd43dad366c908dfdc448f47f8f5b292adc9b93</originalsourceid><addsrcrecordid>eNp9kMtKAzEUhoMoWKsP4C7gempuM5ksS70VChas4C6kubSpnUSSmYI-vVPGjSByFj8c_u_A-QC4xmiCEeK3GWMkWIFwWWDCaMFPwAiXnBYCUXwKRggJXOASvZ2Di5x3CPUUJSOwWm5VapSO7z7Y1mv40nbG2wyjg-3WwnkI8aBaf7BwGlrfdmubdLeP2Wd4l7oNXG19_IrBGwt9gMu9yo26BGdO7bO9-skxeH24X82eisXz43w2XRSact4WrEZE1BQTQStimCKqJiVSFnNnGDXK0KrSAtXGGc1Y7Rh3tSvXRBBltFgLOgY3w92N2lvpg4ttUrrxWcspIwyzqkKsb03-aPVjbON1DNb5fv8LwAOgU8w5WSc_km9U-pQYyaNtOdiWvW15tC15z5CByX03bGySu9il0H__D_QNEZGBkQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Pharmacokinetic Studies of the Innovative Antituberculosis Drug Thiozonide in Plasma</title><source>SpringerLink Journals - AutoHoldings</source><creator>Savchenko, A. Yu ; Men’shikova, L. A. ; Ramenskaya, G. V. ; Smolyarchuk, E. A.</creator><creatorcontrib>Savchenko, A. Yu ; Men’shikova, L. A. ; Ramenskaya, G. V. ; Smolyarchuk, E. A.</creatorcontrib><description>We present here our results from studies of the pharmacokinetic parameters of the original antituberculosis agent thiozonide, 100-mg capsules (ZAO Farm-Sintez, Moscow) using single increasing doses in different groups of healthy volunteers in a phase I clinical trial.</description><identifier>ISSN: 0091-150X</identifier><identifier>EISSN: 1573-9031</identifier><identifier>DOI: 10.1007/s11094-015-1243-7</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Antitubercular agents ; Medicine ; Molecular Biology Problems of Drug Design and Mechanism of Drug Action ; Organic Chemistry ; Pharmacology/Toxicology ; Pharmacy</subject><ispartof>Pharmaceutical chemistry journal, 2015-06, Vol.49 (3), p.147-150</ispartof><rights>Springer Science+Business Media New York 2015</rights><rights>COPYRIGHT 2015 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11094-015-1243-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11094-015-1243-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids></links><search><creatorcontrib>Savchenko, A. Yu</creatorcontrib><creatorcontrib>Men’shikova, L. A.</creatorcontrib><creatorcontrib>Ramenskaya, G. V.</creatorcontrib><creatorcontrib>Smolyarchuk, E. A.</creatorcontrib><title>Pharmacokinetic Studies of the Innovative Antituberculosis Drug Thiozonide in Plasma</title><title>Pharmaceutical chemistry journal</title><addtitle>Pharm Chem J</addtitle><description>We present here our results from studies of the pharmacokinetic parameters of the original antituberculosis agent thiozonide, 100-mg capsules (ZAO Farm-Sintez, Moscow) using single increasing doses in different groups of healthy volunteers in a phase I clinical trial.</description><subject>Antitubercular agents</subject><subject>Medicine</subject><subject>Molecular Biology Problems of Drug Design and Mechanism of Drug Action</subject><subject>Organic Chemistry</subject><subject>Pharmacology/Toxicology</subject><subject>Pharmacy</subject><issn>0091-150X</issn><issn>1573-9031</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp9kMtKAzEUhoMoWKsP4C7gempuM5ksS70VChas4C6kubSpnUSSmYI-vVPGjSByFj8c_u_A-QC4xmiCEeK3GWMkWIFwWWDCaMFPwAiXnBYCUXwKRggJXOASvZ2Di5x3CPUUJSOwWm5VapSO7z7Y1mv40nbG2wyjg-3WwnkI8aBaf7BwGlrfdmubdLeP2Wd4l7oNXG19_IrBGwt9gMu9yo26BGdO7bO9-skxeH24X82eisXz43w2XRSact4WrEZE1BQTQStimCKqJiVSFnNnGDXK0KrSAtXGGc1Y7Rh3tSvXRBBltFgLOgY3w92N2lvpg4ttUrrxWcspIwyzqkKsb03-aPVjbON1DNb5fv8LwAOgU8w5WSc_km9U-pQYyaNtOdiWvW15tC15z5CByX03bGySu9il0H__D_QNEZGBkQ</recordid><startdate>20150601</startdate><enddate>20150601</enddate><creator>Savchenko, A. Yu</creator><creator>Men’shikova, L. A.</creator><creator>Ramenskaya, G. V.</creator><creator>Smolyarchuk, E. A.</creator><general>Springer US</general><general>Springer</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20150601</creationdate><title>Pharmacokinetic Studies of the Innovative Antituberculosis Drug Thiozonide in Plasma</title><author>Savchenko, A. Yu ; Men’shikova, L. A. ; Ramenskaya, G. V. ; Smolyarchuk, E. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c377t-4802983129362d4a2a8250ae17fd43dad366c908dfdc448f47f8f5b292adc9b93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Antitubercular agents</topic><topic>Medicine</topic><topic>Molecular Biology Problems of Drug Design and Mechanism of Drug Action</topic><topic>Organic Chemistry</topic><topic>Pharmacology/Toxicology</topic><topic>Pharmacy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Savchenko, A. Yu</creatorcontrib><creatorcontrib>Men’shikova, L. A.</creatorcontrib><creatorcontrib>Ramenskaya, G. V.</creatorcontrib><creatorcontrib>Smolyarchuk, E. A.</creatorcontrib><collection>CrossRef</collection><jtitle>Pharmaceutical chemistry journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Savchenko, A. Yu</au><au>Men’shikova, L. A.</au><au>Ramenskaya, G. V.</au><au>Smolyarchuk, E. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pharmacokinetic Studies of the Innovative Antituberculosis Drug Thiozonide in Plasma</atitle><jtitle>Pharmaceutical chemistry journal</jtitle><stitle>Pharm Chem J</stitle><date>2015-06-01</date><risdate>2015</risdate><volume>49</volume><issue>3</issue><spage>147</spage><epage>150</epage><pages>147-150</pages><issn>0091-150X</issn><eissn>1573-9031</eissn><abstract>We present here our results from studies of the pharmacokinetic parameters of the original antituberculosis agent thiozonide, 100-mg capsules (ZAO Farm-Sintez, Moscow) using single increasing doses in different groups of healthy volunteers in a phase I clinical trial.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s11094-015-1243-7</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0091-150X
ispartof Pharmaceutical chemistry journal, 2015-06, Vol.49 (3), p.147-150
issn 0091-150X
1573-9031
language eng
recordid cdi_gale_infotracmisc_A424146604
source SpringerLink Journals - AutoHoldings
subjects Antitubercular agents
Medicine
Molecular Biology Problems of Drug Design and Mechanism of Drug Action
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
title Pharmacokinetic Studies of the Innovative Antituberculosis Drug Thiozonide in Plasma
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T09%3A44%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pharmacokinetic%20Studies%20of%20the%20Innovative%20Antituberculosis%20Drug%20Thiozonide%20in%20Plasma&rft.jtitle=Pharmaceutical%20chemistry%20journal&rft.au=Savchenko,%20A.%20Yu&rft.date=2015-06-01&rft.volume=49&rft.issue=3&rft.spage=147&rft.epage=150&rft.pages=147-150&rft.issn=0091-150X&rft.eissn=1573-9031&rft_id=info:doi/10.1007/s11094-015-1243-7&rft_dat=%3Cgale_cross%3EA424146604%3C/gale_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A424146604&rfr_iscdi=true