Another "String to the Bow" of PJ34, a Potent PolyPolymerase Inhibitor: An Antiplatelet Effect through P2Y.sub.12 Antagonism?

Background Neuro- and vasoprotective effects of poly(ADP-ribose)polymerase (PARP) inhibition have been largely documented in models of cerebral ischemia, particularly with the potent PARP inhibitor PJ34. Furthermore, after ischemic stroke, physicians are faced with incomplete tissue reperfusion and...

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Veröffentlicht in:PloS one 2014-10, Vol.9 (10)
Hauptverfasser: Lechaftois, Marie, Dreano, Elise, Palmier, Bruno, Margaill, Isabelle, Marchand-Leroux, Catherine, Bachelot-Loza, Christilla, Lerouet, Dominique
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Sprache:eng
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