Characterization of Albendazole-Randomly Methylated-[beta]-Cyclodextrin Inclusion Complex and In Vivo Evaluation of Its Antihelmitic Activity in a Murine Model of Trichinellosis

Albendazole is a benzimidazole carbamate extensively used in oral chemotherapy against intestinal parasites, due to its broad spectrum activity, good tolerance and low cost. However, the drug has the disadvantage of poor bioavailability due to its very low solubility in water; as a consequence, a ve...

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Veröffentlicht in:PloS one 2014-11, Vol.9 (11)
Hauptverfasser: García, Agustina, Leonardi, Darío, Vasconi, María D, Hinrichsen, Lucila I, Lamas, María C
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Sprache:eng
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