G[α.sub.12] gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) has a poor prognosis owing to aggressive phenotype. G[α.sub.12] gep oncogene product couples to G-protein-coupled receptors, whose ligand levels are frequently increased in tumor microenvironments. Here, we report G[α.sub.12] overexpression in human HCC and the resulta...

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Veröffentlicht in:	Oncogene 2015-05, p.2910
Hauptverfasser:	Yang, Y.M, Lee, W.H, Lee, C.G, An, J, Kim, E.-S, Kim, S.H, Lee, S.-K, Lee, C.H, Dhanasekaran, D.N, Moon, A, Hwang, S, Lee, S.J, Park, J.-W, Kim, K.M, Kim, S.G
Format:	Artikel
Sprache:	eng
Schlagworte:	Development and progression Genetic aspects Genetic regulation Health aspects Hepatoma MicroRNA Properties
Online-Zugang:	Volltext
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