Exogenous Tryptophan Promotes Cutaneous Wound Healing of Chronically Stressed Mice through Inhibition of TNF-[alpha] and IDO Activation

Stress prolongs the inflammatory response compromising the dermal reconstruction and wound closure. Acute stress-induced inflammation increases indoleamine 2, 3-dioxygenase-stimulated tryptophan catabolism. To investigate the role of indoleamine 2, 3-dioxygenase expression and tryptophan administrat...

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Veröffentlicht in:	PloS one 2015-06, Vol.10 (6)
Hauptverfasser:	Bandeira, Luana Graziella, Bortolot, Beatriz Salari, Cecatto, Matheus Jorand, Monte-Alto-Costa, Andréa, Romana-Souza, Bruna
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Collagen Epinephrine Euthanasia Inflammation Skin Tryptophan Tumor necrosis factor Wound care Wound healing
Online-Zugang:	Volltext
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