Virus and autoantigen-specific CD4+ T cells are key effectors in a SCID mouse model of EBV-associated posttransplant lymphoproliferative disorders

Polyclonal Epstein-Barr virus (EBV)-infected B cell line (lymphoblastoid cell lines;LCL)-stimulated T-cell preparations have been successfully used to treat EBV-positive post-transplant lymphoproliferative disorders (PTLD) in transplant recipients, but function and specificity of the CD4+ component...

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Veröffentlicht in:	PLoS pathogens 2014-05, Vol.10 (5)
Hauptverfasser:	Linnerbauer, Stefanie, Behrends, Uta, Adhikary, Dinesh, Witter, Klaus, Bornkamm, Georg W, Mautner, Josef
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Autoimmunity B cells Health aspects Immunotherapy Physiological aspects T cells
Online-Zugang:	Volltext
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