Downregulation of [GABA.sub.A] receptor protein subunits α6, β2, δ, ζ, γ2, θ, and ρ2 in superior frontal cortex of subjects with autism

We measured protein and mRNA levels for nine gamma-aminobutyric acid A ([GABA.sub.A]) receptor subunits in three brain regions (cerebellum, superior frontal cortex, and parietal cortex) in subjects with autism versus matched controls. We observed changes in mRNA for a number of [GABA.sub.A] and [GAB...

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Veröffentlicht in:	Journal of autism and developmental disorders 2014-08, Vol.44 (8), p.1833
Hauptverfasser:	Fatemi, S. Hossein, Reutiman, Teri J, Folsom, Timothy D, Rustan, Oyvind G, Rooney, Robert J, Thuras, Paul D
Format:	Artikel
Sprache:	eng
Schlagworte:	Autism Development and progression GABA Risk factors
Online-Zugang:	Volltext
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