Effect of clonidine added to lidocaine for sub-Tenon’s (episcleral) anesthesia in cataract surgery
Purpose We aimed to evaluate the duration of anesthesia, analgesia and ocular akinesia of clonidine added to lidocaine in sub-Tenon’s anesthesia in patients undergoing cataract surgery. Methods Forty patients were prospectively enrolled. They were randomized to two sub-Tenon’s anesthesia groups: gro...
Gespeichert in:
| Veröffentlicht in: | Journal of anesthesia 2014-02, Vol.28 (1), p.70-75 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 75 |
|---|---|
| container_issue | 1 |
| container_start_page | 70 |
| container_title | Journal of anesthesia |
| container_volume | 28 |
| creator | Cabral, Sigmar Aurea Carraretto, Antonio Roberto Brocco, Marcos Celio Baptista, João Florêncio Abreu Gomez, Renato Santiago |
| description | Purpose
We aimed to evaluate the duration of anesthesia, analgesia and ocular akinesia of clonidine added to lidocaine in sub-Tenon’s anesthesia in patients undergoing cataract surgery.
Methods
Forty patients were prospectively enrolled. They were randomized to two sub-Tenon’s anesthesia groups: group L (6 ml of lidocaine 2 %, 1 ml of 0.9 % saline and 25 UI/ml of hyaluronidase), and group C (6 ml lidocaine 2 %, clonidine 1 μg/kg, 1 ml of 0.9 % saline and 25 UI/ml of hyaluronidase). Duration of sensory anesthesia, ocular akinesia in all directions, akinesia of the levator palpebrae superioris and orbicularis oculi muscles, the duration of analgesia (time to the first postoperative use of analgesics), the overall use of analgesics and the presence of adverse effects were recorded .
Results
The duration of sensory anesthesia and akinesia of the four rectus, levator palpebrae superioris, and orbicularis oculi muscles was significantly longer in group C (
p
|
| doi_str_mv | 10.1007/s00540-013-1660-2 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_cross</sourceid><recordid>TN_cdi_gale_infotracmisc_A372884698</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A372884698</galeid><sourcerecordid>A372884698</sourcerecordid><originalsourceid>FETCH-LOGICAL-c473t-f01cccad465cc22ff5a7e9cd890d09b7c1a66a9727510d685a047d960f66f2063</originalsourceid><addsrcrecordid>eNp9kctKZDEQhsOgaI8zDzAbCbjRRZxKzjm5LEWcCwhunHVI59JGTidNcnrhztfw9XwS0xxHGGiGLAJV3_9TVT9C3yhcUgDxvQIMPRCgHaGcA2Gf0IL2nSSyG9QBWoBqHcm5PEafa30EAE5pd4SOWSeU4KxfIHcTgrcTzgHbMafoYvLYOOcdnjIeo8vW7EohF1y3S3LvU06vzy8Vn_tNrHb0xYwX2CRfpwdfo8ExYWsmU0xzrduy8uXpCzoMZqz-6_t_gv78uLm__kVu737-vr66JbYX3UQCUGutcT0frGUshMEIr6yTChyopbDUcG6UYGKg4LgcDPTCKQ6B88CAdyfobPZdmdHrmEKe2hjrNqa-6gSTsudKNorsoVY-7VbJyYfYyv_wl3v49pxfR7tXQGeBLbnW4oPelLg25UlT0Lvg9BycbsHpXXCaNc3prNlsl2vvPhR_k2oAm4HaWqldVT_mbUntnP9xfQOsw6Lo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Effect of clonidine added to lidocaine for sub-Tenon’s (episcleral) anesthesia in cataract surgery</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Cabral, Sigmar Aurea ; Carraretto, Antonio Roberto ; Brocco, Marcos Celio ; Baptista, João Florêncio Abreu ; Gomez, Renato Santiago</creator><creatorcontrib>Cabral, Sigmar Aurea ; Carraretto, Antonio Roberto ; Brocco, Marcos Celio ; Baptista, João Florêncio Abreu ; Gomez, Renato Santiago</creatorcontrib><description>Purpose
We aimed to evaluate the duration of anesthesia, analgesia and ocular akinesia of clonidine added to lidocaine in sub-Tenon’s anesthesia in patients undergoing cataract surgery.
Methods
Forty patients were prospectively enrolled. They were randomized to two sub-Tenon’s anesthesia groups: group L (6 ml of lidocaine 2 %, 1 ml of 0.9 % saline and 25 UI/ml of hyaluronidase), and group C (6 ml lidocaine 2 %, clonidine 1 μg/kg, 1 ml of 0.9 % saline and 25 UI/ml of hyaluronidase). Duration of sensory anesthesia, ocular akinesia in all directions, akinesia of the levator palpebrae superioris and orbicularis oculi muscles, the duration of analgesia (time to the first postoperative use of analgesics), the overall use of analgesics and the presence of adverse effects were recorded .
Results
The duration of sensory anesthesia and akinesia of the four rectus, levator palpebrae superioris, and orbicularis oculi muscles was significantly longer in group C (
p
< 0.05). The number of patients who required analgesics was similar between the groups but the duration of analgesia was longer in group C (
p
< 0.05). No significant adverse effects were observed.
Conclusion
The addition of clonidine 1 μg/kg to 2 % lidocaine in sub-Tenon’s anesthesia for cataract surgery increased the duration of sensory anesthesia, ocular akinesia, and the duration of analgesia.</description><identifier>ISSN: 0913-8668</identifier><identifier>EISSN: 1438-8359</identifier><identifier>DOI: 10.1007/s00540-013-1660-2</identifier><identifier>PMID: 23797624</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject><![CDATA[Aged ; Analgesics - administration & dosage ; Anesthesia, Local - methods ; Anesthesiology ; Anesthetics, Local - administration & dosage ; Cataract ; Cataract Extraction - methods ; Clonidine ; Clonidine - administration & dosage ; Critical Care Medicine ; Dosage and administration ; Double-Blind Method ; Emergency Medicine ; Evaluation ; Eye Movements - drug effects ; Female ; Humans ; Hyaluronoglucosaminidase - administration & dosage ; Intensive ; Lidocaine ; Lidocaine - administration & dosage ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Original Article ; Pain Medicine ; Prospective Studies ; Surgery]]></subject><ispartof>Journal of anesthesia, 2014-02, Vol.28 (1), p.70-75</ispartof><rights>Japanese Society of Anesthesiologists 2013</rights><rights>COPYRIGHT 2014 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c473t-f01cccad465cc22ff5a7e9cd890d09b7c1a66a9727510d685a047d960f66f2063</citedby><cites>FETCH-LOGICAL-c473t-f01cccad465cc22ff5a7e9cd890d09b7c1a66a9727510d685a047d960f66f2063</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00540-013-1660-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00540-013-1660-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23797624$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cabral, Sigmar Aurea</creatorcontrib><creatorcontrib>Carraretto, Antonio Roberto</creatorcontrib><creatorcontrib>Brocco, Marcos Celio</creatorcontrib><creatorcontrib>Baptista, João Florêncio Abreu</creatorcontrib><creatorcontrib>Gomez, Renato Santiago</creatorcontrib><title>Effect of clonidine added to lidocaine for sub-Tenon’s (episcleral) anesthesia in cataract surgery</title><title>Journal of anesthesia</title><addtitle>J Anesth</addtitle><addtitle>J Anesth</addtitle><description>Purpose
We aimed to evaluate the duration of anesthesia, analgesia and ocular akinesia of clonidine added to lidocaine in sub-Tenon’s anesthesia in patients undergoing cataract surgery.
Methods
Forty patients were prospectively enrolled. They were randomized to two sub-Tenon’s anesthesia groups: group L (6 ml of lidocaine 2 %, 1 ml of 0.9 % saline and 25 UI/ml of hyaluronidase), and group C (6 ml lidocaine 2 %, clonidine 1 μg/kg, 1 ml of 0.9 % saline and 25 UI/ml of hyaluronidase). Duration of sensory anesthesia, ocular akinesia in all directions, akinesia of the levator palpebrae superioris and orbicularis oculi muscles, the duration of analgesia (time to the first postoperative use of analgesics), the overall use of analgesics and the presence of adverse effects were recorded .
Results
The duration of sensory anesthesia and akinesia of the four rectus, levator palpebrae superioris, and orbicularis oculi muscles was significantly longer in group C (
p
< 0.05). The number of patients who required analgesics was similar between the groups but the duration of analgesia was longer in group C (
p
< 0.05). No significant adverse effects were observed.
Conclusion
The addition of clonidine 1 μg/kg to 2 % lidocaine in sub-Tenon’s anesthesia for cataract surgery increased the duration of sensory anesthesia, ocular akinesia, and the duration of analgesia.</description><subject>Aged</subject><subject>Analgesics - administration & dosage</subject><subject>Anesthesia, Local - methods</subject><subject>Anesthesiology</subject><subject>Anesthetics, Local - administration & dosage</subject><subject>Cataract</subject><subject>Cataract Extraction - methods</subject><subject>Clonidine</subject><subject>Clonidine - administration & dosage</subject><subject>Critical Care Medicine</subject><subject>Dosage and administration</subject><subject>Double-Blind Method</subject><subject>Emergency Medicine</subject><subject>Evaluation</subject><subject>Eye Movements - drug effects</subject><subject>Female</subject><subject>Humans</subject><subject>Hyaluronoglucosaminidase - administration & dosage</subject><subject>Intensive</subject><subject>Lidocaine</subject><subject>Lidocaine - administration & dosage</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Original Article</subject><subject>Pain Medicine</subject><subject>Prospective Studies</subject><subject>Surgery</subject><issn>0913-8668</issn><issn>1438-8359</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kctKZDEQhsOgaI8zDzAbCbjRRZxKzjm5LEWcCwhunHVI59JGTidNcnrhztfw9XwS0xxHGGiGLAJV3_9TVT9C3yhcUgDxvQIMPRCgHaGcA2Gf0IL2nSSyG9QBWoBqHcm5PEafa30EAE5pd4SOWSeU4KxfIHcTgrcTzgHbMafoYvLYOOcdnjIeo8vW7EohF1y3S3LvU06vzy8Vn_tNrHb0xYwX2CRfpwdfo8ExYWsmU0xzrduy8uXpCzoMZqz-6_t_gv78uLm__kVu737-vr66JbYX3UQCUGutcT0frGUshMEIr6yTChyopbDUcG6UYGKg4LgcDPTCKQ6B88CAdyfobPZdmdHrmEKe2hjrNqa-6gSTsudKNorsoVY-7VbJyYfYyv_wl3v49pxfR7tXQGeBLbnW4oPelLg25UlT0Lvg9BycbsHpXXCaNc3prNlsl2vvPhR_k2oAm4HaWqldVT_mbUntnP9xfQOsw6Lo</recordid><startdate>20140201</startdate><enddate>20140201</enddate><creator>Cabral, Sigmar Aurea</creator><creator>Carraretto, Antonio Roberto</creator><creator>Brocco, Marcos Celio</creator><creator>Baptista, João Florêncio Abreu</creator><creator>Gomez, Renato Santiago</creator><general>Springer Japan</general><general>Springer</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20140201</creationdate><title>Effect of clonidine added to lidocaine for sub-Tenon’s (episcleral) anesthesia in cataract surgery</title><author>Cabral, Sigmar Aurea ; Carraretto, Antonio Roberto ; Brocco, Marcos Celio ; Baptista, João Florêncio Abreu ; Gomez, Renato Santiago</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c473t-f01cccad465cc22ff5a7e9cd890d09b7c1a66a9727510d685a047d960f66f2063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>Analgesics - administration & dosage</topic><topic>Anesthesia, Local - methods</topic><topic>Anesthesiology</topic><topic>Anesthetics, Local - administration & dosage</topic><topic>Cataract</topic><topic>Cataract Extraction - methods</topic><topic>Clonidine</topic><topic>Clonidine - administration & dosage</topic><topic>Critical Care Medicine</topic><topic>Dosage and administration</topic><topic>Double-Blind Method</topic><topic>Emergency Medicine</topic><topic>Evaluation</topic><topic>Eye Movements - drug effects</topic><topic>Female</topic><topic>Humans</topic><topic>Hyaluronoglucosaminidase - administration & dosage</topic><topic>Intensive</topic><topic>Lidocaine</topic><topic>Lidocaine - administration & dosage</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Original Article</topic><topic>Pain Medicine</topic><topic>Prospective Studies</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cabral, Sigmar Aurea</creatorcontrib><creatorcontrib>Carraretto, Antonio Roberto</creatorcontrib><creatorcontrib>Brocco, Marcos Celio</creatorcontrib><creatorcontrib>Baptista, João Florêncio Abreu</creatorcontrib><creatorcontrib>Gomez, Renato Santiago</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cabral, Sigmar Aurea</au><au>Carraretto, Antonio Roberto</au><au>Brocco, Marcos Celio</au><au>Baptista, João Florêncio Abreu</au><au>Gomez, Renato Santiago</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of clonidine added to lidocaine for sub-Tenon’s (episcleral) anesthesia in cataract surgery</atitle><jtitle>Journal of anesthesia</jtitle><stitle>J Anesth</stitle><addtitle>J Anesth</addtitle><date>2014-02-01</date><risdate>2014</risdate><volume>28</volume><issue>1</issue><spage>70</spage><epage>75</epage><pages>70-75</pages><issn>0913-8668</issn><eissn>1438-8359</eissn><abstract>Purpose
We aimed to evaluate the duration of anesthesia, analgesia and ocular akinesia of clonidine added to lidocaine in sub-Tenon’s anesthesia in patients undergoing cataract surgery.
Methods
Forty patients were prospectively enrolled. They were randomized to two sub-Tenon’s anesthesia groups: group L (6 ml of lidocaine 2 %, 1 ml of 0.9 % saline and 25 UI/ml of hyaluronidase), and group C (6 ml lidocaine 2 %, clonidine 1 μg/kg, 1 ml of 0.9 % saline and 25 UI/ml of hyaluronidase). Duration of sensory anesthesia, ocular akinesia in all directions, akinesia of the levator palpebrae superioris and orbicularis oculi muscles, the duration of analgesia (time to the first postoperative use of analgesics), the overall use of analgesics and the presence of adverse effects were recorded .
Results
The duration of sensory anesthesia and akinesia of the four rectus, levator palpebrae superioris, and orbicularis oculi muscles was significantly longer in group C (
p
< 0.05). The number of patients who required analgesics was similar between the groups but the duration of analgesia was longer in group C (
p
< 0.05). No significant adverse effects were observed.
Conclusion
The addition of clonidine 1 μg/kg to 2 % lidocaine in sub-Tenon’s anesthesia for cataract surgery increased the duration of sensory anesthesia, ocular akinesia, and the duration of analgesia.</abstract><cop>Tokyo</cop><pub>Springer Japan</pub><pmid>23797624</pmid><doi>10.1007/s00540-013-1660-2</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0913-8668 |
| ispartof | Journal of anesthesia, 2014-02, Vol.28 (1), p.70-75 |
| issn | 0913-8668 1438-8359 |
| language | eng |
| recordid | cdi_gale_infotracmisc_A372884698 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Aged Analgesics - administration & dosage Anesthesia, Local - methods Anesthesiology Anesthetics, Local - administration & dosage Cataract Cataract Extraction - methods Clonidine Clonidine - administration & dosage Critical Care Medicine Dosage and administration Double-Blind Method Emergency Medicine Evaluation Eye Movements - drug effects Female Humans Hyaluronoglucosaminidase - administration & dosage Intensive Lidocaine Lidocaine - administration & dosage Male Medicine Medicine & Public Health Middle Aged Original Article Pain Medicine Prospective Studies Surgery |
| title | Effect of clonidine added to lidocaine for sub-Tenon’s (episcleral) anesthesia in cataract surgery |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T03%3A53%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20clonidine%20added%20to%20lidocaine%20for%20sub-Tenon%E2%80%99s%20(episcleral)%20anesthesia%20in%20cataract%20surgery&rft.jtitle=Journal%20of%20anesthesia&rft.au=Cabral,%20Sigmar%20Aurea&rft.date=2014-02-01&rft.volume=28&rft.issue=1&rft.spage=70&rft.epage=75&rft.pages=70-75&rft.issn=0913-8668&rft.eissn=1438-8359&rft_id=info:doi/10.1007/s00540-013-1660-2&rft_dat=%3Cgale_cross%3EA372884698%3C/gale_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/23797624&rft_galeid=A372884698&rfr_iscdi=true |