Estimating the fitness advantage conferred by permissive neuraminidase mutations in recent oseltamivir-resistant Apdm09 influenza viruses

Oseltamivir is relied upon worldwide as the drug of choice for the treatment of human influenza infection. Surveillance for oseltamivir resistance is routinely performed to ensure the ongoing efficacy of oseltamivir against circulating viruses. Since the emergence of the pandemic 2009 A(H1N1) influe...

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Veröffentlicht in:	PLoS pathogens 2014-04, Vol.10 (4)
Hauptverfasser:	Butler, Jeff, Hooper, Kathryn A, Petrie, Stephen, Lee, Raphael, Maurer-Stroh, Sebastian, Reh, Lucia, Guarnaccia, Teagan, Baas, Chantal, Xue, Lumin, Vitesnik, Sophie, Leang, Sook-Kwan, McVernon, Jodie, Kelso, Anne, Barr, Ian G, McCaw, James M, Bloom, Jesse D, Hurt, Aeron C
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene mutations Genetic aspects Genetic research Health aspects Host-parasite relationships Influenza viruses Microbiological research
Online-Zugang:	Volltext
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