'Death and axes': unexpected [Ca.sup.2+] entry phenologs predict new anti-schistosomal agents

Schistosomiasis is a parasitic flatworm disease that infects 200 million people worldwide. The drug praziquantel (PZQ) is the mainstay therapy but the target of this drug remains ambiguous. While PZQ paralyses and kills parasitic schistosomes, in free-living planarians PZQ caused an unusual axis dup...

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Veröffentlicht in:	PLoS pathogens 2014-02, Vol.10 (2)
Hauptverfasser:	Chan, John D, Agbedanu, Prince N, Zamanian, Mostafa, Gruba, Sarah M, Haynes, Christy L, Day, Timothy A, Marchant, Jonathan S
Format:	Artikel
Sprache:	eng
Schlagworte:	Dosage and administration Drug therapy Pharmaceutical research Praziquantel Schistosomiasis
Online-Zugang:	Volltext
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