Synthesis and antimicrobial activity of new phenytoin derivatives and their acyclic nucleoside analogs
New phenytoin derivatives and their N-substituted acyclic nucleoside analogs were prepared. The synthesized compounds were tested for their antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Streptomyces Sp. Most of the tested compounds exhibited moderate to high antimicrobi...
Gespeichert in:
Veröffentlicht in: | Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2012-10, Vol.48 (7), p.1043-1049 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 1049 |
---|---|
container_issue | 7 |
container_start_page | 1043 |
container_title | Chemistry of heterocyclic compounds (New York, N.Y. 1965) |
container_volume | 48 |
creator | Ali, O. M. Amer, H. H. Mosaad, A. A. Abdel-Rahman, A. A.-H. |
description | New phenytoin derivatives and their N-substituted acyclic nucleoside analogs were prepared. The synthesized compounds were tested for their antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Streptomyces Sp. Most of the tested compounds exhibited moderate to high antimicrobial activity while a few compounds were found to exhibit little or no activity against the tested microorganisms. |
doi_str_mv | 10.1007/s10593-012-1097-9 |
format | Article |
fullrecord | <record><control><sourceid>gale_cross</sourceid><recordid>TN_cdi_gale_infotracmisc_A356809137</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A356809137</galeid><sourcerecordid>A356809137</sourcerecordid><originalsourceid>FETCH-LOGICAL-c355t-39c9cd56fa53bb266fc2a3959379e58a7668dfac1a9642af8b58f761ccf3d3eb3</originalsourceid><addsrcrecordid>eNp9kE1rAyEQhqW00PTjB_S20LOtrlHXYwj9gkIPbc_iupoYNhp0k7L_vhO2l0IpIjLO-wzMg9ANJXeUEHlfKOGKYUJrTImSWJ2gGeWS4YZxdopmhBCFGa3rc3RRygZKSZv5DPn3MQ5rV0KpTOzgDmEbbE5tMH1l7BAOYRir5Kvovqrd2sVxSCFWncvhYKDrJg5GhAz50fbBVnFve5dK6Bw0TZ9W5QqdedMXd_3zXqLPx4eP5TN-fXt6WS5esWWcD5gpq2zHhTectW0thLe1YQo2k8rxxkghms4bS40S89r4puWNl4Ja61nHXMsu0e00d2V6p0P0acjGbkOxesG4aIiiTELq7o8UnM7B8ik6H-D_F0AnAMyUkp3Xuxy2Jo-aEn30ryf_Gvzro3-tgKknpkA2rlzWm7TPoKP8A30DwuGJ0A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Synthesis and antimicrobial activity of new phenytoin derivatives and their acyclic nucleoside analogs</title><source>SpringerLink Journals</source><creator>Ali, O. M. ; Amer, H. H. ; Mosaad, A. A. ; Abdel-Rahman, A. A.-H.</creator><creatorcontrib>Ali, O. M. ; Amer, H. H. ; Mosaad, A. A. ; Abdel-Rahman, A. A.-H.</creatorcontrib><description>New phenytoin derivatives and their N-substituted acyclic nucleoside analogs were prepared. The synthesized compounds were tested for their antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Streptomyces Sp. Most of the tested compounds exhibited moderate to high antimicrobial activity while a few compounds were found to exhibit little or no activity against the tested microorganisms.</description><identifier>ISSN: 0009-3122</identifier><identifier>EISSN: 1573-8353</identifier><identifier>DOI: 10.1007/s10593-012-1097-9</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Chemistry ; Chemistry and Materials Science ; Dextrose ; Glucose ; Glucose metabolism ; Nucleoside analogs ; Organic Chemistry ; Pharmacy ; Phenytoin</subject><ispartof>Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2012-10, Vol.48 (7), p.1043-1049</ispartof><rights>Springer Science+Business Media New York 2012</rights><rights>COPYRIGHT 2012 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c355t-39c9cd56fa53bb266fc2a3959379e58a7668dfac1a9642af8b58f761ccf3d3eb3</citedby><cites>FETCH-LOGICAL-c355t-39c9cd56fa53bb266fc2a3959379e58a7668dfac1a9642af8b58f761ccf3d3eb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10593-012-1097-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10593-012-1097-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Ali, O. M.</creatorcontrib><creatorcontrib>Amer, H. H.</creatorcontrib><creatorcontrib>Mosaad, A. A.</creatorcontrib><creatorcontrib>Abdel-Rahman, A. A.-H.</creatorcontrib><title>Synthesis and antimicrobial activity of new phenytoin derivatives and their acyclic nucleoside analogs</title><title>Chemistry of heterocyclic compounds (New York, N.Y. 1965)</title><addtitle>Chem Heterocycl Comp</addtitle><description>New phenytoin derivatives and their N-substituted acyclic nucleoside analogs were prepared. The synthesized compounds were tested for their antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Streptomyces Sp. Most of the tested compounds exhibited moderate to high antimicrobial activity while a few compounds were found to exhibit little or no activity against the tested microorganisms.</description><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Dextrose</subject><subject>Glucose</subject><subject>Glucose metabolism</subject><subject>Nucleoside analogs</subject><subject>Organic Chemistry</subject><subject>Pharmacy</subject><subject>Phenytoin</subject><issn>0009-3122</issn><issn>1573-8353</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp9kE1rAyEQhqW00PTjB_S20LOtrlHXYwj9gkIPbc_iupoYNhp0k7L_vhO2l0IpIjLO-wzMg9ANJXeUEHlfKOGKYUJrTImSWJ2gGeWS4YZxdopmhBCFGa3rc3RRygZKSZv5DPn3MQ5rV0KpTOzgDmEbbE5tMH1l7BAOYRir5Kvovqrd2sVxSCFWncvhYKDrJg5GhAz50fbBVnFve5dK6Bw0TZ9W5QqdedMXd_3zXqLPx4eP5TN-fXt6WS5esWWcD5gpq2zHhTectW0thLe1YQo2k8rxxkghms4bS40S89r4puWNl4Ja61nHXMsu0e00d2V6p0P0acjGbkOxesG4aIiiTELq7o8UnM7B8ik6H-D_F0AnAMyUkp3Xuxy2Jo-aEn30ryf_Gvzro3-tgKknpkA2rlzWm7TPoKP8A30DwuGJ0A</recordid><startdate>20121001</startdate><enddate>20121001</enddate><creator>Ali, O. M.</creator><creator>Amer, H. H.</creator><creator>Mosaad, A. A.</creator><creator>Abdel-Rahman, A. A.-H.</creator><general>Springer US</general><general>Springer</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20121001</creationdate><title>Synthesis and antimicrobial activity of new phenytoin derivatives and their acyclic nucleoside analogs</title><author>Ali, O. M. ; Amer, H. H. ; Mosaad, A. A. ; Abdel-Rahman, A. A.-H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c355t-39c9cd56fa53bb266fc2a3959379e58a7668dfac1a9642af8b58f761ccf3d3eb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Dextrose</topic><topic>Glucose</topic><topic>Glucose metabolism</topic><topic>Nucleoside analogs</topic><topic>Organic Chemistry</topic><topic>Pharmacy</topic><topic>Phenytoin</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ali, O. M.</creatorcontrib><creatorcontrib>Amer, H. H.</creatorcontrib><creatorcontrib>Mosaad, A. A.</creatorcontrib><creatorcontrib>Abdel-Rahman, A. A.-H.</creatorcontrib><collection>CrossRef</collection><jtitle>Chemistry of heterocyclic compounds (New York, N.Y. 1965)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ali, O. M.</au><au>Amer, H. H.</au><au>Mosaad, A. A.</au><au>Abdel-Rahman, A. A.-H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis and antimicrobial activity of new phenytoin derivatives and their acyclic nucleoside analogs</atitle><jtitle>Chemistry of heterocyclic compounds (New York, N.Y. 1965)</jtitle><stitle>Chem Heterocycl Comp</stitle><date>2012-10-01</date><risdate>2012</risdate><volume>48</volume><issue>7</issue><spage>1043</spage><epage>1049</epage><pages>1043-1049</pages><issn>0009-3122</issn><eissn>1573-8353</eissn><abstract>New phenytoin derivatives and their N-substituted acyclic nucleoside analogs were prepared. The synthesized compounds were tested for their antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Streptomyces Sp. Most of the tested compounds exhibited moderate to high antimicrobial activity while a few compounds were found to exhibit little or no activity against the tested microorganisms.</abstract><cop>Boston</cop><pub>Springer US</pub><doi>10.1007/s10593-012-1097-9</doi><tpages>7</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0009-3122 |
ispartof | Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2012-10, Vol.48 (7), p.1043-1049 |
issn | 0009-3122 1573-8353 |
language | eng |
recordid | cdi_gale_infotracmisc_A356809137 |
source | SpringerLink Journals |
subjects | Chemistry Chemistry and Materials Science Dextrose Glucose Glucose metabolism Nucleoside analogs Organic Chemistry Pharmacy Phenytoin |
title | Synthesis and antimicrobial activity of new phenytoin derivatives and their acyclic nucleoside analogs |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T23%3A04%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Synthesis%20and%20antimicrobial%20activity%20of%20new%20phenytoin%20derivatives%20and%20their%20acyclic%20nucleoside%20analogs&rft.jtitle=Chemistry%20of%20heterocyclic%20compounds%20(New%20York,%20N.Y.%201965)&rft.au=Ali,%20O.%20M.&rft.date=2012-10-01&rft.volume=48&rft.issue=7&rft.spage=1043&rft.epage=1049&rft.pages=1043-1049&rft.issn=0009-3122&rft.eissn=1573-8353&rft_id=info:doi/10.1007/s10593-012-1097-9&rft_dat=%3Cgale_cross%3EA356809137%3C/gale_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A356809137&rfr_iscdi=true |