Synthesis and antimicrobial activity of new phenytoin derivatives and their acyclic nucleoside analogs

New phenytoin derivatives and their N-substituted acyclic nucleoside analogs were prepared. The synthesized compounds were tested for their antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Streptomyces Sp. Most of the tested compounds exhibited moderate to high antimicrobi...

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Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2012-10, Vol.48 (7), p.1043-1049
Hauptverfasser: Ali, O. M., Amer, H. H., Mosaad, A. A., Abdel-Rahman, A. A.-H.
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container_issue 7
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container_title Chemistry of heterocyclic compounds (New York, N.Y. 1965)
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creator Ali, O. M.
Amer, H. H.
Mosaad, A. A.
Abdel-Rahman, A. A.-H.
description New phenytoin derivatives and their N-substituted acyclic nucleoside analogs were prepared. The synthesized compounds were tested for their antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Streptomyces Sp. Most of the tested compounds exhibited moderate to high antimicrobial activity while a few compounds were found to exhibit little or no activity against the tested microorganisms.
doi_str_mv 10.1007/s10593-012-1097-9
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ispartof Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2012-10, Vol.48 (7), p.1043-1049
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subjects Chemistry
Chemistry and Materials Science
Dextrose
Glucose
Glucose metabolism
Nucleoside analogs
Organic Chemistry
Pharmacy
Phenytoin
title Synthesis and antimicrobial activity of new phenytoin derivatives and their acyclic nucleoside analogs
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