Effects of Liquid Crystal Systems Based on Cholesterol Esters on Skin Permeability

The mechanisms of the influences of liquid crystal systems based on cholesterol esters on skin permeability were investigated. The effects of liquid crystal systems based on cholesterol esters on the transcutaneous penetration of phenazepam from transdermal therapeutic patches were studied in in vit...

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Veröffentlicht in:Pharmaceutical chemistry journal 2013-10, Vol.47 (7), p.393-396
Hauptverfasser: Boiko, Yu. A., Kravchenko, I. A., Novikova, N. S., Egorova, A. V., Aleksandrova, D. I.
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container_issue 7
container_start_page 393
container_title Pharmaceutical chemistry journal
container_volume 47
creator Boiko, Yu. A.
Kravchenko, I. A.
Novikova, N. S.
Egorova, A. V.
Aleksandrova, D. I.
description The mechanisms of the influences of liquid crystal systems based on cholesterol esters on skin permeability were investigated. The effects of liquid crystal systems based on cholesterol esters on the transcutaneous penetration of phenazepam from transdermal therapeutic patches were studied in in vitro conditions. Changes in the fluidity of phospholipid liposomes and liposomes prepared from stratum corneum lipids were studied using fluorescence spectroscopy. Liquid crystal systems based on cholesterol were shown to be effective enhancers of skin permeability.
doi_str_mv 10.1007/s11094-013-0966-6
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subjects Acrylic acid
Blood lipids
Cholesterol
Esters
Fluorescence
Medicine
Organic Chemistry
Permeability
Pharmacology/Toxicology
Pharmacy
Skin
title Effects of Liquid Crystal Systems Based on Cholesterol Esters on Skin Permeability
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