Effects of Liquid Crystal Systems Based on Cholesterol Esters on Skin Permeability
The mechanisms of the influences of liquid crystal systems based on cholesterol esters on skin permeability were investigated. The effects of liquid crystal systems based on cholesterol esters on the transcutaneous penetration of phenazepam from transdermal therapeutic patches were studied in in vit...
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Veröffentlicht in: | Pharmaceutical chemistry journal 2013-10, Vol.47 (7), p.393-396 |
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creator | Boiko, Yu. A. Kravchenko, I. A. Novikova, N. S. Egorova, A. V. Aleksandrova, D. I. |
description | The mechanisms of the influences of liquid crystal systems based on cholesterol esters on skin permeability were investigated. The effects of liquid crystal systems based on cholesterol esters on the transcutaneous penetration of phenazepam from transdermal therapeutic patches were studied in in vitro conditions. Changes in the fluidity of phospholipid liposomes and liposomes prepared from stratum corneum lipids were studied using fluorescence spectroscopy. Liquid crystal systems based on cholesterol were shown to be effective enhancers of skin permeability. |
doi_str_mv | 10.1007/s11094-013-0966-6 |
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A. ; Kravchenko, I. A. ; Novikova, N. S. ; Egorova, A. V. ; Aleksandrova, D. I.</creator><creatorcontrib>Boiko, Yu. A. ; Kravchenko, I. A. ; Novikova, N. S. ; Egorova, A. V. ; Aleksandrova, D. I.</creatorcontrib><description>The mechanisms of the influences of liquid crystal systems based on cholesterol esters on skin permeability were investigated. The effects of liquid crystal systems based on cholesterol esters on the transcutaneous penetration of phenazepam from transdermal therapeutic patches were studied in in vitro conditions. Changes in the fluidity of phospholipid liposomes and liposomes prepared from stratum corneum lipids were studied using fluorescence spectroscopy. Liquid crystal systems based on cholesterol were shown to be effective enhancers of skin permeability.</description><identifier>ISSN: 0091-150X</identifier><identifier>EISSN: 1573-9031</identifier><identifier>DOI: 10.1007/s11094-013-0966-6</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Acrylic acid ; Blood lipids ; Cholesterol ; Esters ; Fluorescence ; Medicine ; Organic Chemistry ; Permeability ; Pharmacology/Toxicology ; Pharmacy ; Skin</subject><ispartof>Pharmaceutical chemistry journal, 2013-10, Vol.47 (7), p.393-396</ispartof><rights>Springer Science+Business Media New York 2013</rights><rights>COPYRIGHT 2013 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c355t-3b92765c91acf7ed58ddd6a903dfc80eefb33dfa993c7c4c33358fd36cc7ed393</citedby><cites>FETCH-LOGICAL-c355t-3b92765c91acf7ed58ddd6a903dfc80eefb33dfa993c7c4c33358fd36cc7ed393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11094-013-0966-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11094-013-0966-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Boiko, Yu. 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Liquid crystal systems based on cholesterol were shown to be effective enhancers of skin permeability.</description><subject>Acrylic acid</subject><subject>Blood lipids</subject><subject>Cholesterol</subject><subject>Esters</subject><subject>Fluorescence</subject><subject>Medicine</subject><subject>Organic Chemistry</subject><subject>Permeability</subject><subject>Pharmacology/Toxicology</subject><subject>Pharmacy</subject><subject>Skin</subject><issn>0091-150X</issn><issn>1573-9031</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp9kEtLAzEUhYMoWKs_wF3AdWoyaTKTZR3qAwqKVXAX0jxq6sxEk-mi_94M40YQyeKEw_ku9x4ALgmeEYzL60QIFnOECUVYcI74EZgQVlIkMCXHYIKxIIgw_HYKzlLaYZwpWkzA89I5q_sEg4Mr_7X3BtbxkHrVwHUW2yZ4o5I1MHSwfg-NzV4MDVwOmgZ3_eE7-GRja9XGN74_nIMTp5pkL350Cl5vly_1PVo93j3UixXSlLEe0Y0oSs60IEq70hpWGWO4yvsapytsrdvQ_FVCUF3quaaUssoZyrXOaSroFFyNc7eqsdJ3LvRR6dYnLReUFdVclBzn1OyPVH7Gtl6Hzjqf_V8AGQEdQ0rROvkZfaviQRIsh67l2LXMXcuha8kzU4xMytlua6PchX3s8vX_QN8Mn4F_</recordid><startdate>20131001</startdate><enddate>20131001</enddate><creator>Boiko, Yu. 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The effects of liquid crystal systems based on cholesterol esters on the transcutaneous penetration of phenazepam from transdermal therapeutic patches were studied in in vitro conditions. Changes in the fluidity of phospholipid liposomes and liposomes prepared from stratum corneum lipids were studied using fluorescence spectroscopy. Liquid crystal systems based on cholesterol were shown to be effective enhancers of skin permeability.</abstract><cop>Boston</cop><pub>Springer US</pub><doi>10.1007/s11094-013-0966-6</doi><tpages>4</tpages></addata></record> |
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subjects | Acrylic acid Blood lipids Cholesterol Esters Fluorescence Medicine Organic Chemistry Permeability Pharmacology/Toxicology Pharmacy Skin |
title | Effects of Liquid Crystal Systems Based on Cholesterol Esters on Skin Permeability |
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