Synthesis and Structure of Dimephosphone Pyridinoylhydrazones with Antimycobacterial Activity

Nicotinoyl- and isonicotinoylhydrazones of 2-dimethoxyphosphoryl-2-methylpentan-4-one (the active ingredient of the medicinal preparation Dimephosphone) were synthesized. It was shown that crystals of both hydrazones contained a single spatial form of the E C=N isomer. The dimephosphone pyridinoylhy...

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Veröffentlicht in:	Pharmaceutical chemistry journal 2013-04, Vol.47 (1), p.35-39
Hauptverfasser:	Buzykin, B. I., Nabiullin, V. N., Garaev, R. S., Chestnova, R. V., Kashapov, L. R., Valeev, R. Sh, Mironov, V. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitubercular agents Medicine Nuclear magnetic resonance spectroscopy Organic Chemistry Pharmacology/Toxicology Pharmacy
Online-Zugang:	Volltext
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