T lymphocytes from chagasic patients are activated but lack proliferative capacity and down-regulate CD28 and CD3θ

Background: Chronic persistent infections have been associated with T lymphocytes functional impairment. The aim of this study was to compare the activation status, the proliferative potential and the expression of CD28 and CD3θ chain on T lymphocytes between chronic chagasic patients and uninfected...

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Veröffentlicht in:	PLoS neglected tropical diseases 2013-01, Vol.7 (1)
Hauptverfasser:	Giraldo, Nicolas A, Bolanos, Natalia I, Cuellar, Adriana, Roa, Nubi a, Cucunuba, Zulma, Rosas, Fernando, Velasco, Victor, Puerta, Concepcion J, Gonzalez, John M
Format:	Artikel
Sprache:	eng
Schlagworte:	Chagas' disease Genetic aspects Health aspects Prevention T cells
Online-Zugang:	Volltext
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