Antimicrobial susceptibility of Staphylococcus pseudintermedius isolated from dogs and cats in Croatia during a six-month period/Osjetljivost na antibiotike bakterije Staphylococcus pseudintermedius izdvojene iz pasa i macaka u Hrvatskoj tijekom razdoblja od sest mjeseci

Staphylococcus pseudintermedius is part of the normal flora of dogs but is also commonly found as an opportunistic pathogen. Antimicrobial resistance in S. pseudintermedius is changing over time and is generally rising steadily for those antimicrobials that are frequently used. In this work, the sus...

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Veröffentlicht in:Veterinarski arhiv 2012-09, Vol.82 (5), p.505
Hauptverfasser: Matanovic, Kresimir, Mekic, Selma, Seol, Branka
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Seol, Branka
description Staphylococcus pseudintermedius is part of the normal flora of dogs but is also commonly found as an opportunistic pathogen. Antimicrobial resistance in S. pseudintermedius is changing over time and is generally rising steadily for those antimicrobials that are frequently used. In this work, the susceptibility of 106 canine and feline isolates of S. pseudintermedius was determined by the disk-diffusion method. Isolates were collected from various body sites of diseased dogs and cats during a six-month period in 2011. Most isolates were susceptible to amoxycillin/clavulanic acid, cephalexin, enrofloxacin and oxacillin (92.5%), followed by trimethoprimsulfamethoxazole (90.6%) and gentamicin (82.1%). Lower susceptibility was found for minocycline (67.0%), erythromycin, clindamycin and tetracycline (62.3%) and kanamycin (58.5%). Only 21.7% of the isolates were susceptible to ampicillin. Susceptibilities of isolates were compared from different isolation sites and from different temporal origins. The possible association of resistances to different antimicrobial agents is discussed. Key words: Staphylococcus pseudintermedius, antimicrobial resistance, disk-diffusion method Bakterija Staphylococcus pseudintermedius dio je fizioloske mikroflore pasa, ali i cest uzrocnik oportunistickih zaraza. Kod ove je bakterije primjetan trend porasta rezistencije na antimikrobne lijekove koji se ucestalo koriste u lijecenju pasa. U ovom radu istrazena je osjetljivost na antimikrobne lijekove 106 izolata bakterije S. pseudintermedius izdvojenih iz pasa i macaka. Osjetljivost je odrecena disk-difuzijskim postupkom. Izolaci su potjecali od bolesnih pasa i macaka i prikupljeni su u razdoblju od sest mjeseci tijekom godine 2011. Vecina izolata bila je osjetljiva na amoksicilin s klavulanskom kiselinom, cefaleksin, enrofloksacin i oksacilin (92,5%), sulfametoksazol s trimetoprimom (90,6%) i gentamicin (82,1%). Nizi postotak osjetljivosti utvrcenje za minociklin (67,0%), eritromicin, klindamicin i tetraciklin (62,3%) te kanamicin (58,5%). Samo 21,7% izolata bilo je osjetljivo na ampicilin. U radu je usporedena ucestalost rezistencije izmecu izolata izdvojenih s koze i iz zvukovoda, a istrazene su i razlike u rezistenciji u odnosu na prijasnje istrazivanje provedeno u Hrvatskoj. Raspravlja se i o mogucoj povezanosti izmecu rezistencija na razlicite antimikrobne lijekove. Kljucne rijeci: Staphylococcus pseudintermedius, rezistencija, disk-difuzijski postupak
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Antimicrobial resistance in S. pseudintermedius is changing over time and is generally rising steadily for those antimicrobials that are frequently used. In this work, the susceptibility of 106 canine and feline isolates of S. pseudintermedius was determined by the disk-diffusion method. Isolates were collected from various body sites of diseased dogs and cats during a six-month period in 2011. Most isolates were susceptible to amoxycillin/clavulanic acid, cephalexin, enrofloxacin and oxacillin (92.5%), followed by trimethoprimsulfamethoxazole (90.6%) and gentamicin (82.1%). Lower susceptibility was found for minocycline (67.0%), erythromycin, clindamycin and tetracycline (62.3%) and kanamycin (58.5%). Only 21.7% of the isolates were susceptible to ampicillin. Susceptibilities of isolates were compared from different isolation sites and from different temporal origins. The possible association of resistances to different antimicrobial agents is discussed. Key words: Staphylococcus pseudintermedius, antimicrobial resistance, disk-diffusion method Bakterija Staphylococcus pseudintermedius dio je fizioloske mikroflore pasa, ali i cest uzrocnik oportunistickih zaraza. Kod ove je bakterije primjetan trend porasta rezistencije na antimikrobne lijekove koji se ucestalo koriste u lijecenju pasa. U ovom radu istrazena je osjetljivost na antimikrobne lijekove 106 izolata bakterije S. pseudintermedius izdvojenih iz pasa i macaka. Osjetljivost je odrecena disk-difuzijskim postupkom. Izolaci su potjecali od bolesnih pasa i macaka i prikupljeni su u razdoblju od sest mjeseci tijekom godine 2011. Vecina izolata bila je osjetljiva na amoksicilin s klavulanskom kiselinom, cefaleksin, enrofloksacin i oksacilin (92,5%), sulfametoksazol s trimetoprimom (90,6%) i gentamicin (82,1%). Nizi postotak osjetljivosti utvrcenje za minociklin (67,0%), eritromicin, klindamicin i tetraciklin (62,3%) te kanamicin (58,5%). Samo 21,7% izolata bilo je osjetljivo na ampicilin. U radu je usporedena ucestalost rezistencije izmecu izolata izdvojenih s koze i iz zvukovoda, a istrazene su i razlike u rezistenciji u odnosu na prijasnje istrazivanje provedeno u Hrvatskoj. Raspravlja se i o mogucoj povezanosti izmecu rezistencija na razlicite antimikrobne lijekove. 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Antimicrobial resistance in S. pseudintermedius is changing over time and is generally rising steadily for those antimicrobials that are frequently used. In this work, the susceptibility of 106 canine and feline isolates of S. pseudintermedius was determined by the disk-diffusion method. Isolates were collected from various body sites of diseased dogs and cats during a six-month period in 2011. Most isolates were susceptible to amoxycillin/clavulanic acid, cephalexin, enrofloxacin and oxacillin (92.5%), followed by trimethoprimsulfamethoxazole (90.6%) and gentamicin (82.1%). Lower susceptibility was found for minocycline (67.0%), erythromycin, clindamycin and tetracycline (62.3%) and kanamycin (58.5%). Only 21.7% of the isolates were susceptible to ampicillin. Susceptibilities of isolates were compared from different isolation sites and from different temporal origins. The possible association of resistances to different antimicrobial agents is discussed. 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Samo 21,7% izolata bilo je osjetljivo na ampicilin. U radu je usporedena ucestalost rezistencije izmecu izolata izdvojenih s koze i iz zvukovoda, a istrazene su i razlike u rezistenciji u odnosu na prijasnje istrazivanje provedeno u Hrvatskoj. Raspravlja se i o mogucoj povezanosti izmecu rezistencija na razlicite antimikrobne lijekove. 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Antimicrobial resistance in S. pseudintermedius is changing over time and is generally rising steadily for those antimicrobials that are frequently used. In this work, the susceptibility of 106 canine and feline isolates of S. pseudintermedius was determined by the disk-diffusion method. Isolates were collected from various body sites of diseased dogs and cats during a six-month period in 2011. Most isolates were susceptible to amoxycillin/clavulanic acid, cephalexin, enrofloxacin and oxacillin (92.5%), followed by trimethoprimsulfamethoxazole (90.6%) and gentamicin (82.1%). Lower susceptibility was found for minocycline (67.0%), erythromycin, clindamycin and tetracycline (62.3%) and kanamycin (58.5%). Only 21.7% of the isolates were susceptible to ampicillin. Susceptibilities of isolates were compared from different isolation sites and from different temporal origins. The possible association of resistances to different antimicrobial agents is discussed. Key words: Staphylococcus pseudintermedius, antimicrobial resistance, disk-diffusion method Bakterija Staphylococcus pseudintermedius dio je fizioloske mikroflore pasa, ali i cest uzrocnik oportunistickih zaraza. Kod ove je bakterije primjetan trend porasta rezistencije na antimikrobne lijekove koji se ucestalo koriste u lijecenju pasa. U ovom radu istrazena je osjetljivost na antimikrobne lijekove 106 izolata bakterije S. pseudintermedius izdvojenih iz pasa i macaka. Osjetljivost je odrecena disk-difuzijskim postupkom. Izolaci su potjecali od bolesnih pasa i macaka i prikupljeni su u razdoblju od sest mjeseci tijekom godine 2011. Vecina izolata bila je osjetljiva na amoksicilin s klavulanskom kiselinom, cefaleksin, enrofloksacin i oksacilin (92,5%), sulfametoksazol s trimetoprimom (90,6%) i gentamicin (82,1%). Nizi postotak osjetljivosti utvrcenje za minociklin (67,0%), eritromicin, klindamicin i tetraciklin (62,3%) te kanamicin (58,5%). Samo 21,7% izolata bilo je osjetljivo na ampicilin. U radu je usporedena ucestalost rezistencije izmecu izolata izdvojenih s koze i iz zvukovoda, a istrazene su i razlike u rezistenciji u odnosu na prijasnje istrazivanje provedeno u Hrvatskoj. Raspravlja se i o mogucoj povezanosti izmecu rezistencija na razlicite antimikrobne lijekove. Kljucne rijeci: Staphylococcus pseudintermedius, rezistencija, disk-difuzijski postupak</abstract><pub>Sveuciliste U Zagrebu</pub></addata></record>
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subjects Anti-infective agents
Canidae
Felidae
Health aspects
Physiological aspects
Staphylococcus
title Antimicrobial susceptibility of Staphylococcus pseudintermedius isolated from dogs and cats in Croatia during a six-month period/Osjetljivost na antibiotike bakterije Staphylococcus pseudintermedius izdvojene iz pasa i macaka u Hrvatskoj tijekom razdoblja od sest mjeseci
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