Extrathymically generated regulatory T cells control mucosal TH2 inflammation

A balance between pro- and anti-inflammatory mechanisms at mucosal interfaces, which are sites of constitutive exposure to microbes and non-microbial foreign substances, allows for efficient protection against pathogens yet prevents adverse inflammatory responses associated with allergy, asthma and...

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Veröffentlicht in:Nature (London) 2012-02, Vol.482 (7385), p.395
Hauptverfasser: Josefowicz, Steven Z, Niec, Rachel E, Kim, Hye Young, Treuting, Piper, Chinen, Takatoshi, Zheng, Ye, Umetsu, Dale T, Rudensky, Alexander Y
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Sprache:eng
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