Suppression of Fox01 activity by long-chain fatty acyl analogs.(Forkhead transcription factor)

OBJECTIVE--Overactivity of the Forkhead transcription factor FoxO1 promotes diabetic hyperglycemia, dyslipidemia, and acutephase response, whereas suppression of FoxO1 activity by insulin may alleviate diabetes. The reported efficacy of long-chain fatty acyl (LCFA) analogs of the MEDICA series in ac...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2011-07, Vol.60 (7), p.1872
Hauptverfasser:	Zatara, Ghadeer, Hertz, Rachel, Shaked, Maayan, Mayorek, Nina, Morad, Etedal, Grad, Etty, Cahan, Amos, Danenberg, Haim D, Unterman, Terry G, Bar-Tana, Jacob
Format:	Artikel
Sprache:	eng
Schlagworte:	Fatty acids Genetic aspects Hyperglycemia Physiological aspects Risk factors Transcription factors
Online-Zugang:	Volltext
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