COX-2-dependent [PGE.sub.2] acts as a growth factor in mycosis fungoides (MF)

Cancer often originates from a site of persistent inflammation, and the mechanisms turning chronic inflammation into a driving force of carcinogenesis are intensely investigated. Cyclooxygenase-2 (COX-2) is an inducible key modulator of inflammation that carries out the rate-limiting step in prostag...

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Veröffentlicht in:	Leukemia 2010-06, Vol.24 (6), p.1179
Hauptverfasser:	Kopp, K.L.M, Kauczok, C.S, Lauenborg, B, Krejsgaard, T, Eriksen, K.W, Zhang, Q, Wasik, M.A, Geisler, C, Ralfkiaer, E, Becker, J.C, Odum, N, Woetmann, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell proliferation Cutaneous T cell lymphoma Cyclooxygenases Development and progression Diagnosis Genetic aspects Mycosis fungoides Prostaglandins Prostaglandins E Synthesis
Online-Zugang:	Volltext
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