4[beta]-Hydroxywithanolide E from Physalis peruviana inhibits growth of human lung cancer cells through DNA damage, apoptosis and G.sub.2 /M arrest

Background The crude extract of the fruit bearing plant, Physalis peruviana (golden berry), demonstrated anti-hepatoma and anti-inflammatory activities. However, the cellular mechanism involved in this process is still unknown. Methods Herein, we isolated the main pure compound, 4[beta]-Hydroxywitha...

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Veröffentlicht in:	BMC cancer 2010-02, Vol.10, p.46
Hauptverfasser:	Yen, Ching-Yu, Chiu, Chien-Chih, Chang, Fang-Rong, Chen, Jeff Yi-Fu, Hwang, Chi-Ching, Hseu, You-Cheng, Yang, Hsin-Ling, Lee, Alan Yueh-Luen, Tsai, Ming-Tz, Guo, Zong-Lun, Cheng, Yu-Shan, Liu, Yin-Chang, Lan, Yu-Hsuan, Chang, Yu-Ching, Ko, Ying-Chin, Chang, Hsueh-Wei, Wu, Yang-Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Berries Care and treatment Causes of DNA damage Genetic aspects Health aspects Lung cancer Physiological aspects
Online-Zugang:	Volltext
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