Strong genetic evidence for a selective influence of [GABA.sub.A] receptors on a component of the bipolar disorder phenotype

Despite compelling evidence for a major genetic contribution to risk of bipolar mood disorder, conclusive evidence implicating specific genes or pathophysiological systems has proved elusive. In part this is likely to be related to the unknown validity of current phenotype definitions and consequent...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular psychiatry 2010-02, Vol.15 (2), p.146
Hauptverfasser:	Craddock, N, Jones, L, Jones, I.R, Kirov, G, Green, E.K, Grozeva, D, Moskvina, V, Nikolov, I, Hamshere, M.L, Vukcevic, D, Caesar, S, Gordon-Smith, K, Fraser, C, Russell, E, Norton, N, Breen, G, St. Clair, D, Collier, D.A, Young, A.H, Ferrier, I.N, Farmer, A, McGuffin, P, Holmans, P.A, Donnelly, P, Owen, M.J, O'Donovan, M.C
Format:	Artikel
Sprache:	eng
Schlagworte:	Bipolar disorder GABA Genetic aspects Genetic susceptibility Receptors Risk factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!