Enteric defensins are essential regulators of intestinal microbial ecology

Antimicrobial peptides are important effectors of innate immunity throughout the plant and animal kingdoms. In the mammalian small intestine, Paneth cell α-defensins are antimicrobial peptides that contribute to host defense against enteric pathogens. To determine if α-defensins also govern intestin...

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Veröffentlicht in:	Nature immunology 2010-01, Vol.11 (1), p.76
Hauptverfasser:	Salzman, Nita H, Hung, Kuiechun, Haribhai, Dipica, Chu, Hiutung, Karlsson-Sjoberg, Jenny, Amir, Elad, Teggatz, Paul, Barman, Melissa, Hayward, Michael, Eastwood, Daniel, Stoel, Maaike, Zhou, Yanjiao, Sodergren, Erica, Weinstock, George M, Bevins, Charles L, Williams, Calvin B, Bos, Nicolaas A
Format:	Artikel
Sprache:	eng
Schlagworte:	Genetic aspects Health aspects Interleukins Mice Microbiota (Symbiotic organisms) Natural immunity
Online-Zugang:	Volltext
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