Increased expression of TLR7 in [CD8.sup.+] T cells leads to TLR7-mediated activation and accessory cell-dependent IFN-γ production in HIV type 1 infection

It has recently been demonstrated that toll-like receptors (TLRs) can recognize structural conserved motifs carried by circulating microbial products and lead to systemic immune responses in individuals infected with HIV-1. TLRs have been detected in [CD8.sup.+] T cells at either a protein or RNA le...

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Veröffentlicht in:	AIDS research and human retroviruses 2009-12, Vol.25 (12), p.1287
Hauptverfasser:	Song, Yang, Zhuang, Yan, Zhai, Song, Huang, Dedong, Zhang, Ying, Kang, Wenzhen, Li, Xinhong, Liu, Qingquan, Yu, Qigui, Sun, Yongtao
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell receptors Health aspects HIV infection Immune response Interferon gamma Physiological aspects Risk factors T cells
Online-Zugang:	Volltext
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