Skin manifestations of chronic hepatitis C virus infection in Cairo, Egypt/ Manifestations cutanees de l'infection chronique par le virus de l'hepatite C au Caire (Egypte)
We assessed the dermatological manifestations associated with chronic hepatitis C virus (HCV) infection and their association with liver status. Of 155 patients with chronic HCV infection in Cairo, Egypt, 71 (45.8%) had dermatological manifestations: pruritus without evident skin lesions (21.3%), pi...
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Veröffentlicht in: | Eastern Mediterranean health journal 2009-05, Vol.15 (3), p.692 |
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Zusammenfassung: | We assessed the dermatological manifestations associated with chronic hepatitis C virus (HCV) infection and their association with liver status. Of 155 patients with chronic HCV infection in Cairo, Egypt, 71 (45.8%) had dermatological manifestations: pruritus without evident skin lesions (21.3%), pigmented purpuric eruption (5.2%), aphthous ulcer and lichen planus (3.9% each), leukocytoclastic vasculitis (2.6%), psoriasis (1.9%), tinea versicolor (1.3%) and other conditions (5.8%). Shrunken liver, splenomegaly and ascites were significantly associated with the presence of skin lesions (relative risk 8.0, 2.7 and 1.8 respectively), and shrunken liver was significantly associated with pruritus (relative risk 2.1). Sex was not associated with any of the skin lesions. Nous avons passe en revue les manifestations dermatologiques liees a l'infection chronique par le virus de l'hepatite C (VHC) et leur rapport avec l'etat hepatique. Sur 155 patients atteints de cette infection au Caire (Egypte), 71 (45,8 %) presentaient des manifestations dermatologiques : prurit sans lesions cutanees evidentes (21,3 %), eruption purpurique pigmentee (5,2 %), ulcere aphteux et lichen plan (3,9 % chacun), vascularite leucocytoclasique (2,6 %), psoriasis (1,9 %), pityriasis versicolor (1,3 %) et autres affections (5,8 %). L'atrophie hepatique, la splenomegalie et l'ascite etaient significativement associees a la presence de lesions cutanees (risque relatif : respectivement 8,0, 2,7 et 1,8) et l'atrophie hepatique seule etait significativement associee au prurit (risque relatif : 2,1). Le sexe n'etait associe a aucune des lesions cutanees. |
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ISSN: | 1020-3397 |