Possible role of TORCH agents in congenital malformations in Gorgan, northern Islamic Republic of Iran/Role possible des agents TORCH dans les malformations congenitales a Gorgan (nord de la Republique islamique d'Iran)
This descriptive, cross-sectional study was carried out to explore the frequency of contamination with TORCH agents in neonates with congenital malformations in a referral centre in Gorgan city, Islamic Republic of Iran. Blood samples were taken from 64 neonates and their mothers over a 20-month per...
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| Veröffentlicht in: | Eastern Mediterranean health journal 2009-03, Vol.15 (2), p.330 |
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| description | This descriptive, cross-sectional study was carried out to explore the frequency of contamination with TORCH agents in neonates with congenital malformations in a referral centre in Gorgan city, Islamic Republic of Iran. Blood samples were taken from 64 neonates and their mothers over a 20-month period in 2003-04. Serologic tests showed that 4/64 infants born with congenital malformations (6%) had positive IgM antibody titres for Toxoplasma gondii (2 cases), rubella virus (1 case) and cytomegalovirus (1 case). IgM was positive in 9/63 mothers (14%), also for T. gondii (3 cases), rubella virus (3 cases) and cytomegalovirus (3 cases). No cases of herpes simplex virus type II or Treponema pallidum were found. [TEXT NOT REPRODUCIBLE IN ASCII] Cette etude descriptive transversale a ete realisee afin d'examiner la frequence de la contamination par les agents TORCH chez les nouveau-nes presentant des malformations congenitales dans un centre specialise de Gorgan (Republique islamique d'Iran). Des prelevements sanguins ont ete effectues sur 64 nouveau-nes et leur mere pendant une periode de 20 mois en 2003-2004. Les tests serologiques ont montre que quatre nourrissons sur 64 nes avec des malformations congenitales (6 %) avaient des taux positifs d'anticorps de type IgM diriges contre Toxoplasma gondii (2 cas), contre le virus de la rubeole (un cas) et contre le cytomegalovirus (un cas). Chez neuf meres sur 63 (14 %), les IgM etaient positifs a T. gondii (trois cas), au virus de la rubeole (trois cas) et au cytomegalovirus (trois cas). Aucun cas de virus de l'herpes de type 2 ou de Treponema pallidum n'a ete detecte. |
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Blood samples were taken from 64 neonates and their mothers over a 20-month period in 2003-04. Serologic tests showed that 4/64 infants born with congenital malformations (6%) had positive IgM antibody titres for Toxoplasma gondii (2 cases), rubella virus (1 case) and cytomegalovirus (1 case). IgM was positive in 9/63 mothers (14%), also for T. gondii (3 cases), rubella virus (3 cases) and cytomegalovirus (3 cases). No cases of herpes simplex virus type II or Treponema pallidum were found. [TEXT NOT REPRODUCIBLE IN ASCII] Cette etude descriptive transversale a ete realisee afin d'examiner la frequence de la contamination par les agents TORCH chez les nouveau-nes presentant des malformations congenitales dans un centre specialise de Gorgan (Republique islamique d'Iran). Des prelevements sanguins ont ete effectues sur 64 nouveau-nes et leur mere pendant une periode de 20 mois en 2003-2004. Les tests serologiques ont montre que quatre nourrissons sur 64 nes avec des malformations congenitales (6 %) avaient des taux positifs d'anticorps de type IgM diriges contre Toxoplasma gondii (2 cas), contre le virus de la rubeole (un cas) et contre le cytomegalovirus (un cas). Chez neuf meres sur 63 (14 %), les IgM etaient positifs a T. gondii (trois cas), au virus de la rubeole (trois cas) et au cytomegalovirus (trois cas). Aucun cas de virus de l'herpes de type 2 ou de Treponema pallidum n'a ete detecte.</description><identifier>ISSN: 1020-3397</identifier><language>eng</language><publisher>World Health Organization</publisher><subject>Anti-infective agents ; Birth defects ; Complications and side effects ; Demographic aspects ; Diagnosis ; Health aspects ; Medical examination ; Pregnant women ; Risk factors</subject><ispartof>Eastern Mediterranean health journal, 2009-03, Vol.15 (2), p.330</ispartof><rights>COPYRIGHT 2009 World Health Organization</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Golalipour, M.J</creatorcontrib><creatorcontrib>Khodabakhshi, B</creatorcontrib><creatorcontrib>Ghaemi, E</creatorcontrib><title>Possible role of TORCH agents in congenital malformations in Gorgan, northern Islamic Republic of Iran/Role possible des agents TORCH dans les malformations congenitales a Gorgan (nord de la Republique islamique d'Iran)</title><title>Eastern Mediterranean health journal</title><description>This descriptive, cross-sectional study was carried out to explore the frequency of contamination with TORCH agents in neonates with congenital malformations in a referral centre in Gorgan city, Islamic Republic of Iran. Blood samples were taken from 64 neonates and their mothers over a 20-month period in 2003-04. Serologic tests showed that 4/64 infants born with congenital malformations (6%) had positive IgM antibody titres for Toxoplasma gondii (2 cases), rubella virus (1 case) and cytomegalovirus (1 case). IgM was positive in 9/63 mothers (14%), also for T. gondii (3 cases), rubella virus (3 cases) and cytomegalovirus (3 cases). No cases of herpes simplex virus type II or Treponema pallidum were found. [TEXT NOT REPRODUCIBLE IN ASCII] Cette etude descriptive transversale a ete realisee afin d'examiner la frequence de la contamination par les agents TORCH chez les nouveau-nes presentant des malformations congenitales dans un centre specialise de Gorgan (Republique islamique d'Iran). Des prelevements sanguins ont ete effectues sur 64 nouveau-nes et leur mere pendant une periode de 20 mois en 2003-2004. Les tests serologiques ont montre que quatre nourrissons sur 64 nes avec des malformations congenitales (6 %) avaient des taux positifs d'anticorps de type IgM diriges contre Toxoplasma gondii (2 cas), contre le virus de la rubeole (un cas) et contre le cytomegalovirus (un cas). Chez neuf meres sur 63 (14 %), les IgM etaient positifs a T. gondii (trois cas), au virus de la rubeole (trois cas) et au cytomegalovirus (trois cas). Aucun cas de virus de l'herpes de type 2 ou de Treponema pallidum n'a ete detecte.</description><subject>Anti-infective agents</subject><subject>Birth defects</subject><subject>Complications and side effects</subject><subject>Demographic aspects</subject><subject>Diagnosis</subject><subject>Health aspects</subject><subject>Medical examination</subject><subject>Pregnant women</subject><subject>Risk factors</subject><issn>1020-3397</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>KPI</sourceid><recordid>eNptkF1LwzAUhnuh4Jz-h4CgDqy2ST8vx9CtONgY83qcNkkXSZPZtOB_9c-Y7gNXkEByOHnf9zmcC2fge9hzCUnjK-famE_Pw0kS4IHzs9TGiFwyVGt7aY7Wi9VkhqBkqjFIKFRoZWvRgEQVSK7rChqh1f5vqusS1BNSum62rFYoMxIqUaAV27W5tIUNzGpQL6sufXdiUWZOhAOOgg2UtttH_LE7wxGHHi2O2gwk4QT6ahkSe3ZX0YeOObpxLjlIw26P79D5eHtdT2bufDHNJuO5W_oExy6kPA-BBAxHuY8JpHEeERbHUZIUeYADD7hHqE98CEmYsjiiNA-DICoi8D2eFmTo3B1ySzvnRiiumxqKSphiM8Z279YaxVb1_I_KHsrsxrRiXNh-zzDqGaymYd9NCa0xm_dl1tfen2m3DGSzNVq2-zWeC38BXE6lcg</recordid><startdate>20090301</startdate><enddate>20090301</enddate><creator>Golalipour, M.J</creator><creator>Khodabakhshi, B</creator><creator>Ghaemi, E</creator><general>World Health Organization</general><scope>KPI</scope></search><sort><creationdate>20090301</creationdate><title>Possible role of TORCH agents in congenital malformations in Gorgan, northern Islamic Republic of Iran/Role possible des agents TORCH dans les malformations congenitales a Gorgan (nord de la Republique islamique d'Iran)</title><author>Golalipour, M.J ; Khodabakhshi, B ; Ghaemi, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g1327-a9fb5a34e26b123a97b63e77688cb4240af03d131a5359e76ddb5446c6a10f9c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Anti-infective agents</topic><topic>Birth defects</topic><topic>Complications and side effects</topic><topic>Demographic aspects</topic><topic>Diagnosis</topic><topic>Health aspects</topic><topic>Medical examination</topic><topic>Pregnant women</topic><topic>Risk factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Golalipour, M.J</creatorcontrib><creatorcontrib>Khodabakhshi, B</creatorcontrib><creatorcontrib>Ghaemi, E</creatorcontrib><collection>Gale In Context: Global Issues</collection><jtitle>Eastern Mediterranean health journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Golalipour, M.J</au><au>Khodabakhshi, B</au><au>Ghaemi, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Possible role of TORCH agents in congenital malformations in Gorgan, northern Islamic Republic of Iran/Role possible des agents TORCH dans les malformations congenitales a Gorgan (nord de la Republique islamique d'Iran)</atitle><jtitle>Eastern Mediterranean health journal</jtitle><date>2009-03-01</date><risdate>2009</risdate><volume>15</volume><issue>2</issue><spage>330</spage><pages>330-</pages><issn>1020-3397</issn><abstract>This descriptive, cross-sectional study was carried out to explore the frequency of contamination with TORCH agents in neonates with congenital malformations in a referral centre in Gorgan city, Islamic Republic of Iran. Blood samples were taken from 64 neonates and their mothers over a 20-month period in 2003-04. Serologic tests showed that 4/64 infants born with congenital malformations (6%) had positive IgM antibody titres for Toxoplasma gondii (2 cases), rubella virus (1 case) and cytomegalovirus (1 case). IgM was positive in 9/63 mothers (14%), also for T. gondii (3 cases), rubella virus (3 cases) and cytomegalovirus (3 cases). No cases of herpes simplex virus type II or Treponema pallidum were found. [TEXT NOT REPRODUCIBLE IN ASCII] Cette etude descriptive transversale a ete realisee afin d'examiner la frequence de la contamination par les agents TORCH chez les nouveau-nes presentant des malformations congenitales dans un centre specialise de Gorgan (Republique islamique d'Iran). Des prelevements sanguins ont ete effectues sur 64 nouveau-nes et leur mere pendant une periode de 20 mois en 2003-2004. Les tests serologiques ont montre que quatre nourrissons sur 64 nes avec des malformations congenitales (6 %) avaient des taux positifs d'anticorps de type IgM diriges contre Toxoplasma gondii (2 cas), contre le virus de la rubeole (un cas) et contre le cytomegalovirus (un cas). Chez neuf meres sur 63 (14 %), les IgM etaient positifs a T. gondii (trois cas), au virus de la rubeole (trois cas) et au cytomegalovirus (trois cas). Aucun cas de virus de l'herpes de type 2 ou de Treponema pallidum n'a ete detecte.</abstract><pub>World Health Organization</pub><tpages>7</tpages></addata></record> |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Anti-infective agents Birth defects Complications and side effects Demographic aspects Diagnosis Health aspects Medical examination Pregnant women Risk factors |
| title | Possible role of TORCH agents in congenital malformations in Gorgan, northern Islamic Republic of Iran/Role possible des agents TORCH dans les malformations congenitales a Gorgan (nord de la Republique islamique d'Iran) |
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