Blimp-1 over Budapest: Blimp-1 is a transcription factor that affects the expression of hundreds of genes in lymphocytes. Recent work confirmed its role in the maturation of B cells into immunoglobulin-secreting plasmablasts, as well as in the control of T cell homeostasis and tolerance. What follows is a short history of how Blimp-1 was discovered
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Veröffentlicht in: | Nature immunology 2007-05, Vol.8 (5), p.445 |
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subjects | DNA binding proteins Genes Genetic aspects Lymphocytes Physiological aspects |
title | Blimp-1 over Budapest: Blimp-1 is a transcription factor that affects the expression of hundreds of genes in lymphocytes. Recent work confirmed its role in the maturation of B cells into immunoglobulin-secreting plasmablasts, as well as in the control of T cell homeostasis and tolerance. What follows is a short history of how Blimp-1 was discovered |
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