Homeostasis of αβ TCR + T cells
Cytokines contribute to T cell homeostasis at all stages of T cell existence. However, the particular cytokine involved varies as T cells progress from a naïve through an activated to a memory state. In many cases the important cytokines are members of the interleukin 2 subfamily of the short-chain...
Gespeichert in:
| Veröffentlicht in: | Nature immunology 2000-08, Vol.1 (2), p.107-111 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 111 |
|---|---|
| container_issue | 2 |
| container_start_page | 107 |
| container_title | Nature immunology |
| container_volume | 1 |
| creator | Marrack, Philippa Bender, Jeremy Hildeman, David Jordan, Michael Mitchell, Tom Murakami, Masaaki Sakamoto, Akemi Schaefer, Brian C Swanson, Bradley Kappler, John |
| description | Cytokines contribute to T cell homeostasis at all stages of T cell existence. However, the particular cytokine involved varies as T cells progress from a naïve through an activated to a memory state. In many cases the important cytokines are members of the interleukin 2 subfamily of the short-chain type I cytokines. A case is made for the idea that the evolutionary divergence of the short-chain family allowed for concurrent divergence in leukocytes. |
| doi_str_mv | 10.1038/77778 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_cross</sourceid><recordid>TN_cdi_gale_infotracmisc_A188805706</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A188805706</galeid><sourcerecordid>A188805706</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2918-b17c03f19c78748bbbc548ada1bd37783f55336603e955a71f42a6d8bd9190433</originalsourceid><addsrcrecordid>eNpt0GFLAyEYB3CJgtbadzCiIOKWzvP0Xo5RbTAI1notnqfDcXeG3qB9rPog-0y5Lgaj9IWiv-dR_gAMMBpiRPgDi4OfgB6mozwZ5Tg7PewRPwcXIawRwinL0h64mrpau9DKYAN0Bu4-d19wOVnAe7iESldVuARnRlZBD37XPnh7elxOpsn85Xk2Gc8TFZ_gSYGZQsTgXDHOUl4UhaIpl6XERUnif4ihlJAsQ0TnlEqGTTqSWcmLMsc5Sgnpg-uu70pWWtjGuNZLVdugxBhzzhFlKItq-I-Ks9S1Va7Rxsbzo4K7o4JoWv3RruQmBDF7XRzbm84q70Lw2oh3b2vptwIjsY9W_EQb3W3nQrxvVtqLtdv4JqbzB8IONrLdeH1o11jE0V4y8g3bdn1u</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Homeostasis of αβ TCR + T cells</title><source>Nature</source><source>SpringerNature Journals</source><creator>Marrack, Philippa ; Bender, Jeremy ; Hildeman, David ; Jordan, Michael ; Mitchell, Tom ; Murakami, Masaaki ; Sakamoto, Akemi ; Schaefer, Brian C ; Swanson, Bradley ; Kappler, John</creator><creatorcontrib>Marrack, Philippa ; Bender, Jeremy ; Hildeman, David ; Jordan, Michael ; Mitchell, Tom ; Murakami, Masaaki ; Sakamoto, Akemi ; Schaefer, Brian C ; Swanson, Bradley ; Kappler, John</creatorcontrib><description>Cytokines contribute to T cell homeostasis at all stages of T cell existence. However, the particular cytokine involved varies as T cells progress from a naïve through an activated to a memory state. In many cases the important cytokines are members of the interleukin 2 subfamily of the short-chain type I cytokines. A case is made for the idea that the evolutionary divergence of the short-chain family allowed for concurrent divergence in leukocytes.</description><identifier>ISSN: 1529-2908</identifier><identifier>EISSN: 1529-2916</identifier><identifier>DOI: 10.1038/77778</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>Biomedical and Life Sciences ; Biomedicine ; Immunology ; Infectious Diseases ; review-article</subject><ispartof>Nature immunology, 2000-08, Vol.1 (2), p.107-111</ispartof><rights>Nature America Inc. 2000</rights><rights>COPYRIGHT 2000 Nature Publishing Group</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2918-b17c03f19c78748bbbc548ada1bd37783f55336603e955a71f42a6d8bd9190433</citedby><cites>FETCH-LOGICAL-c2918-b17c03f19c78748bbbc548ada1bd37783f55336603e955a71f42a6d8bd9190433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/77778$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/77778$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,2727,27924,27925,41488,42557,51319</link.rule.ids></links><search><creatorcontrib>Marrack, Philippa</creatorcontrib><creatorcontrib>Bender, Jeremy</creatorcontrib><creatorcontrib>Hildeman, David</creatorcontrib><creatorcontrib>Jordan, Michael</creatorcontrib><creatorcontrib>Mitchell, Tom</creatorcontrib><creatorcontrib>Murakami, Masaaki</creatorcontrib><creatorcontrib>Sakamoto, Akemi</creatorcontrib><creatorcontrib>Schaefer, Brian C</creatorcontrib><creatorcontrib>Swanson, Bradley</creatorcontrib><creatorcontrib>Kappler, John</creatorcontrib><title>Homeostasis of αβ TCR + T cells</title><title>Nature immunology</title><addtitle>Nat Immunol</addtitle><description>Cytokines contribute to T cell homeostasis at all stages of T cell existence. However, the particular cytokine involved varies as T cells progress from a naïve through an activated to a memory state. In many cases the important cytokines are members of the interleukin 2 subfamily of the short-chain type I cytokines. A case is made for the idea that the evolutionary divergence of the short-chain family allowed for concurrent divergence in leukocytes.</description><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Immunology</subject><subject>Infectious Diseases</subject><subject>review-article</subject><issn>1529-2908</issn><issn>1529-2916</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><recordid>eNpt0GFLAyEYB3CJgtbadzCiIOKWzvP0Xo5RbTAI1notnqfDcXeG3qB9rPog-0y5Lgaj9IWiv-dR_gAMMBpiRPgDi4OfgB6mozwZ5Tg7PewRPwcXIawRwinL0h64mrpau9DKYAN0Bu4-d19wOVnAe7iESldVuARnRlZBD37XPnh7elxOpsn85Xk2Gc8TFZ_gSYGZQsTgXDHOUl4UhaIpl6XERUnif4ihlJAsQ0TnlEqGTTqSWcmLMsc5Sgnpg-uu70pWWtjGuNZLVdugxBhzzhFlKItq-I-Ks9S1Va7Rxsbzo4K7o4JoWv3RruQmBDF7XRzbm84q70Lw2oh3b2vptwIjsY9W_EQb3W3nQrxvVtqLtdv4JqbzB8IONrLdeH1o11jE0V4y8g3bdn1u</recordid><startdate>200008</startdate><enddate>200008</enddate><creator>Marrack, Philippa</creator><creator>Bender, Jeremy</creator><creator>Hildeman, David</creator><creator>Jordan, Michael</creator><creator>Mitchell, Tom</creator><creator>Murakami, Masaaki</creator><creator>Sakamoto, Akemi</creator><creator>Schaefer, Brian C</creator><creator>Swanson, Bradley</creator><creator>Kappler, John</creator><general>Nature Publishing Group US</general><general>Nature Publishing Group</general><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope></search><sort><creationdate>200008</creationdate><title>Homeostasis of αβ TCR + T cells</title><author>Marrack, Philippa ; Bender, Jeremy ; Hildeman, David ; Jordan, Michael ; Mitchell, Tom ; Murakami, Masaaki ; Sakamoto, Akemi ; Schaefer, Brian C ; Swanson, Bradley ; Kappler, John</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2918-b17c03f19c78748bbbc548ada1bd37783f55336603e955a71f42a6d8bd9190433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Immunology</topic><topic>Infectious Diseases</topic><topic>review-article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Marrack, Philippa</creatorcontrib><creatorcontrib>Bender, Jeremy</creatorcontrib><creatorcontrib>Hildeman, David</creatorcontrib><creatorcontrib>Jordan, Michael</creatorcontrib><creatorcontrib>Mitchell, Tom</creatorcontrib><creatorcontrib>Murakami, Masaaki</creatorcontrib><creatorcontrib>Sakamoto, Akemi</creatorcontrib><creatorcontrib>Schaefer, Brian C</creatorcontrib><creatorcontrib>Swanson, Bradley</creatorcontrib><creatorcontrib>Kappler, John</creatorcontrib><collection>CrossRef</collection><collection>Gale In Context: Science</collection><jtitle>Nature immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Marrack, Philippa</au><au>Bender, Jeremy</au><au>Hildeman, David</au><au>Jordan, Michael</au><au>Mitchell, Tom</au><au>Murakami, Masaaki</au><au>Sakamoto, Akemi</au><au>Schaefer, Brian C</au><au>Swanson, Bradley</au><au>Kappler, John</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Homeostasis of αβ TCR + T cells</atitle><jtitle>Nature immunology</jtitle><stitle>Nat Immunol</stitle><date>2000-08</date><risdate>2000</risdate><volume>1</volume><issue>2</issue><spage>107</spage><epage>111</epage><pages>107-111</pages><issn>1529-2908</issn><eissn>1529-2916</eissn><abstract>Cytokines contribute to T cell homeostasis at all stages of T cell existence. However, the particular cytokine involved varies as T cells progress from a naïve through an activated to a memory state. In many cases the important cytokines are members of the interleukin 2 subfamily of the short-chain type I cytokines. A case is made for the idea that the evolutionary divergence of the short-chain family allowed for concurrent divergence in leukocytes.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><doi>10.1038/77778</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1529-2908 |
| ispartof | Nature immunology, 2000-08, Vol.1 (2), p.107-111 |
| issn | 1529-2908 1529-2916 |
| language | eng |
| recordid | cdi_gale_infotracmisc_A188805706 |
| source | Nature; SpringerNature Journals |
| subjects | Biomedical and Life Sciences Biomedicine Immunology Infectious Diseases review-article |
| title | Homeostasis of αβ TCR + T cells |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T20%3A34%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Homeostasis%20of%20%CE%B1%CE%B2%20TCR%20+%20T%20cells&rft.jtitle=Nature%20immunology&rft.au=Marrack,%20Philippa&rft.date=2000-08&rft.volume=1&rft.issue=2&rft.spage=107&rft.epage=111&rft.pages=107-111&rft.issn=1529-2908&rft.eissn=1529-2916&rft_id=info:doi/10.1038/77778&rft_dat=%3Cgale_cross%3EA188805706%3C/gale_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A188805706&rfr_iscdi=true |