A robust and high-capacity [[sup.35]S]GTPγS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine [H.sub.3] receptor ligands

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Veröffentlicht in:Assay and drug development technologies 2008-06, Vol.6 (3), p.339
Hauptverfasser: Miller, Thomas R, Baranowski, John L, Estvander, Brian R, Witte, David G, Carr, Tracy L, Manelli, Arlene M, Krueger, Kathleen M, Cowart, Marlon D, Brioni, Jorge D, Esbenshade, Timothy A
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creator Miller, Thomas R
Baranowski, John L
Estvander, Brian R
Witte, David G
Carr, Tracy L
Manelli, Arlene M
Krueger, Kathleen M
Cowart, Marlon D
Brioni, Jorge D
Esbenshade, Timothy A
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subjects Analysis
DNA binding proteins
Gene expression
Imidazole
Pharmacokinetics
title A robust and high-capacity [[sup.35]S]GTPγS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine [H.sub.3] receptor ligands
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