Transcription factor FOXO3a controls the persistence of memory [CD4.sup.+} T cells during HIV infection

The persistence of central memory [CD4.sup.+} T cells ([T.sub.CM] cells) is a major correlate of immunological protection in HIV/AIDS, as the rate of [T.sub.CM] cell decline predicts HIV disease progression. In this study, we show that [T.sub.CM] cells and effector memory [CD4.sup.+} T cells ([T.sub...

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Veröffentlicht in:Nature medicine 2008-03, Vol.14 (3), p.266
Hauptverfasser: van Grevenynghe, Julien, Procopio, Francesco A, He, Zhong, Chomont, Nicolas, Riou, Catherine, Zhang, Yuwei, Gimmig, Sylvain, Boucher, Genevieve, Wilkinson, Peter, Shi, Yu, Yassine-Diab, Bader, Said, Elias A, Trautmann, Lydie, Far, Mohamed El, Balderas, Robert S, Boulassel, Mohamed-Rachid, Routy, Jean-Pierre, Haddad, Elias K, Sekaly, Rafick-Pierre
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Sprache:eng
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