Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult Mouse Islets In Vivo

Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult Mouse Islets In Vivo Yingda Wang 1 , Brian P. Flemming 1 , Cyrus C. Martin 1 , Shelley R. Allen 1 , Jay Walters 2 , James K. Oeser 1 , John C. H...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2008-01, Vol.57 (1), p.133-141
Hauptverfasser:	Wang, Yingda, Flemming, Brian P, Martin, Cyrus C, Allen, Shelley R, Walters, Jay, Oeser, James K, Hutton, John C, O'Brien, Richard M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Artificial chromosomes beta-Galactosidase - genetics Chromosomes, Artificial, Bacterial Cloning, Molecular Diabetes Diabetes Mellitus, Type 1 - genetics Enhancer Elements, Genetic Gene expression Gene Expression Regulation Genes, Reporter Genetic aspects Glucose Glucose-6-phosphatase Glucose-6-Phosphatase - genetics Islet cell stimulating antibodies Islets of Langerhans - physiology Laboratory animals Luciferases - genetics Metabolism Mice Mice, Transgenic Phosphatase Physiological aspects Promoter Regions, Genetic Proteins Proteins - genetics Research design Stem cells Transcription factors Transfection Transgenic animals Type 1 diabetes
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