[p57.sup.KIP2] expression in normal islet cells and in hyperinsulinism of infancy

Most cases of hyperinsulinism of infancy (HI) are caused by mutations in either the sulfonylurea receptor-1 (SUR1) or the inward rectifying [K.sup.+] channel Kir6.2, two subunits of the [beta]-cell ATP-sensitive [K.sup.+] channel ([K.sub.ATP] channel). Histologically, HI can be divided into two majo...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2001-12, Vol.50 (12), p.2763
Hauptverfasser:	Kassem, S.A, Ariel, I, Thornton, P.S, Hussain, K, Smith, V, Lindley, K.J, Aynsley-Green, A, Glaser, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Genetic research Health aspects Infants Metabolic diseases Risk factors
Online-Zugang:	Volltext
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