COURSES OF SUBSTANCE USE AND SCHIZOPHRENIA IN THE DUAL-DIAGNOSIS PATIENTS: IS THERE A RELATIONSHIP?
Background: Interrelationship of schizophrenia and substance use is complex and multifactorial. Examining the influence of various psychoactive substances on course of patients with dual-diagnosis schizophrenia may help to solve this riddle. Aim: To examine the relationship of the courses of substan...
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| Veröffentlicht in: | Indian journal of medical sciences 2003-08, Vol.57 (8), p.338 |
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| creator | S Goswami, G Singh, S K Mattoo, D Basu |
| description | Background: Interrelationship of schizophrenia and substance use is
complex and multifactorial. Examining the influence of various
psychoactive substances on course of patients with dual-diagnosis
schizophrenia may help to solve this riddle. Aim: To examine the
relationship of the courses of substance use and schizophrenic
symptomatology in substance abusing "dual-diagnosis" patients with
schizophrenia. Settings and Design: Outpatient Deaddiction and
Treatment Center of a tertiary care hospital with; retrospective
design. Methods and Material: Twenty-two substance abusing
dual-diagnosis patients with schizophrenia were investigated regarding
the course of substance use (abuse/dependence, use, non-use) and that
of schizophrenia (psychotic, non-psychotic, in remission). A graphical
representation of course of schizophrenia and substance abuse was made
and their relationship studied by superimposition of respective graphs.
Statistics : The Friedman two-way analysis of variance of ranks was
applied to see the relationship between time spent by patients while on
and off various substances. Results: In five cases, the onset of
schizophrenia preceded the onset of substance use. In seven out of 22
subjects, the schizophrenic exacerbation was clearly preceded by
increase in substance abuse in the preceding 2-12 months. In none of
the subjects decrease in substance use led to a decrease or increase in
schizophrenic symptoms. Conclusions: Although substance use disorder
preceded the onset of schizophrenic illness in the majority, and
increase in substance abuse preceded schizophrenic exacerbation in
one-third of dual-diagnosis patients, overall there was no evidence
that the course of substance use was associated with that of
schizophrenia after both disorders were diagnosed. |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_gale_infotracgeneralonefile_A110115761</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A110115761</galeid><sourcerecordid>A110115761</sourcerecordid><originalsourceid>FETCH-LOGICAL-b238t-299f33c861158b0bcb2ed3b4f09c67c5c0ecd96d03c44c9fd726ca6bba5d90c3</originalsourceid><addsrcrecordid>eNptkMtugzAQRVm0atK0v1D5B6hsDE7cTUWJEyxFEGHYdIP8IqICEkG66N_XUvrYRDPSaO7cexZz480hRNSPcERn3v00fUAY4CCCd94MBTQMCYVzTyd5VQgmQL4BonoTZZwlDFSCgThbA5Gk_D3fpwXLeAx4BsqUgXUV7_w1j7dZLrgA-7jkLCvFC3CLuxcuCgq2c3KeiZTvXx-820Z2k338mQuv3LAySf1dvuWJg6kAr85-QGmDsV4RhKKVgkqrwBqswgZSTZY60tBqQ4mBWIehpo1ZBkRLopSMDIUaLzz_gj3Iztbt0BzPo9QHO9hRdsfBNq2TY4Sg4y8Jcv7nK35Xxvatvhp4ugROn6q3pj6NbS_Hr_r3m_9E1R67drB_Dj22sv4V-8k1xI6KvwGoi3fB</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>COURSES OF SUBSTANCE USE AND SCHIZOPHRENIA IN THE DUAL-DIAGNOSIS PATIENTS: IS THERE A RELATIONSHIP?</title><source>MEDLINE</source><source>Bioline International</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>S Goswami, G Singh, S K Mattoo, D Basu</creator><creatorcontrib>S Goswami, G Singh, S K Mattoo, D Basu</creatorcontrib><description>Background: Interrelationship of schizophrenia and substance use is
complex and multifactorial. Examining the influence of various
psychoactive substances on course of patients with dual-diagnosis
schizophrenia may help to solve this riddle. Aim: To examine the
relationship of the courses of substance use and schizophrenic
symptomatology in substance abusing "dual-diagnosis" patients with
schizophrenia. Settings and Design: Outpatient Deaddiction and
Treatment Center of a tertiary care hospital with; retrospective
design. Methods and Material: Twenty-two substance abusing
dual-diagnosis patients with schizophrenia were investigated regarding
the course of substance use (abuse/dependence, use, non-use) and that
of schizophrenia (psychotic, non-psychotic, in remission). A graphical
representation of course of schizophrenia and substance abuse was made
and their relationship studied by superimposition of respective graphs.
Statistics : The Friedman two-way analysis of variance of ranks was
applied to see the relationship between time spent by patients while on
and off various substances. Results: In five cases, the onset of
schizophrenia preceded the onset of substance use. In seven out of 22
subjects, the schizophrenic exacerbation was clearly preceded by
increase in substance abuse in the preceding 2-12 months. In none of
the subjects decrease in substance use led to a decrease or increase in
schizophrenic symptoms. Conclusions: Although substance use disorder
preceded the onset of schizophrenic illness in the majority, and
increase in substance abuse preceded schizophrenic exacerbation in
one-third of dual-diagnosis patients, overall there was no evidence
that the course of substance use was associated with that of
schizophrenia after both disorders were diagnosed.</description><identifier>ISSN: 0019-5359</identifier><identifier>PMID: 12944690</identifier><language>eng</language><publisher>India: Medknow Publications on behalf of Indian Journal of Medical Sciences Trust</publisher><subject>Adolescent ; Adult ; Age of Onset ; Alcoholism - epidemiology ; Behavior ; Comorbidity ; Diagnosis, Dual (Psychiatry) ; Disease Progression ; Dual diagnosis ; Humans ; India - epidemiology ; Male ; Marijuana Abuse - epidemiology ; Middle Aged ; Opioid-Related Disorders - epidemiology ; Remission, Spontaneous ; Retrospective Studies ; Risk factors ; Schizophrenia - diagnosis ; Schizophrenia - epidemiology ; Schizophrenia, Course, Dual-diagnosis ; Schizophrenics ; Socioeconomic Factors ; Statistics ; Substance abuse ; Substance-Related Disorders - diagnosis ; Substance-Related Disorders - epidemiology ; Time Factors</subject><ispartof>Indian journal of medical sciences, 2003-08, Vol.57 (8), p.338</ispartof><rights>Copyright 2003 - Indian Journal of Medical Sciences.</rights><rights>COPYRIGHT 2003 Medknow Publications and Media Pvt. Ltd.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,79168</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12944690$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>S Goswami, G Singh, S K Mattoo, D Basu</creatorcontrib><title>COURSES OF SUBSTANCE USE AND SCHIZOPHRENIA IN THE DUAL-DIAGNOSIS PATIENTS: IS THERE A RELATIONSHIP?</title><title>Indian journal of medical sciences</title><addtitle>Indian J Med Sci</addtitle><description>Background: Interrelationship of schizophrenia and substance use is
complex and multifactorial. Examining the influence of various
psychoactive substances on course of patients with dual-diagnosis
schizophrenia may help to solve this riddle. Aim: To examine the
relationship of the courses of substance use and schizophrenic
symptomatology in substance abusing "dual-diagnosis" patients with
schizophrenia. Settings and Design: Outpatient Deaddiction and
Treatment Center of a tertiary care hospital with; retrospective
design. Methods and Material: Twenty-two substance abusing
dual-diagnosis patients with schizophrenia were investigated regarding
the course of substance use (abuse/dependence, use, non-use) and that
of schizophrenia (psychotic, non-psychotic, in remission). A graphical
representation of course of schizophrenia and substance abuse was made
and their relationship studied by superimposition of respective graphs.
Statistics : The Friedman two-way analysis of variance of ranks was
applied to see the relationship between time spent by patients while on
and off various substances. Results: In five cases, the onset of
schizophrenia preceded the onset of substance use. In seven out of 22
subjects, the schizophrenic exacerbation was clearly preceded by
increase in substance abuse in the preceding 2-12 months. In none of
the subjects decrease in substance use led to a decrease or increase in
schizophrenic symptoms. Conclusions: Although substance use disorder
preceded the onset of schizophrenic illness in the majority, and
increase in substance abuse preceded schizophrenic exacerbation in
one-third of dual-diagnosis patients, overall there was no evidence
that the course of substance use was associated with that of
schizophrenia after both disorders were diagnosed.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age of Onset</subject><subject>Alcoholism - epidemiology</subject><subject>Behavior</subject><subject>Comorbidity</subject><subject>Diagnosis, Dual (Psychiatry)</subject><subject>Disease Progression</subject><subject>Dual diagnosis</subject><subject>Humans</subject><subject>India - epidemiology</subject><subject>Male</subject><subject>Marijuana Abuse - epidemiology</subject><subject>Middle Aged</subject><subject>Opioid-Related Disorders - epidemiology</subject><subject>Remission, Spontaneous</subject><subject>Retrospective Studies</subject><subject>Risk factors</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenia - epidemiology</subject><subject>Schizophrenia, Course, Dual-diagnosis</subject><subject>Schizophrenics</subject><subject>Socioeconomic Factors</subject><subject>Statistics</subject><subject>Substance abuse</subject><subject>Substance-Related Disorders - diagnosis</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Time Factors</subject><issn>0019-5359</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>RBI</sourceid><sourceid>EIF</sourceid><recordid>eNptkMtugzAQRVm0atK0v1D5B6hsDE7cTUWJEyxFEGHYdIP8IqICEkG66N_XUvrYRDPSaO7cexZz480hRNSPcERn3v00fUAY4CCCd94MBTQMCYVzTyd5VQgmQL4BonoTZZwlDFSCgThbA5Gk_D3fpwXLeAx4BsqUgXUV7_w1j7dZLrgA-7jkLCvFC3CLuxcuCgq2c3KeiZTvXx-820Z2k338mQuv3LAySf1dvuWJg6kAr85-QGmDsV4RhKKVgkqrwBqswgZSTZY60tBqQ4mBWIehpo1ZBkRLopSMDIUaLzz_gj3Iztbt0BzPo9QHO9hRdsfBNq2TY4Sg4y8Jcv7nK35Xxvatvhp4ugROn6q3pj6NbS_Hr_r3m_9E1R67drB_Dj22sv4V-8k1xI6KvwGoi3fB</recordid><startdate>200308</startdate><enddate>200308</enddate><creator>S Goswami, G Singh, S K Mattoo, D Basu</creator><general>Medknow Publications on behalf of Indian Journal of Medical Sciences Trust</general><general>Medknow Publications and Media Pvt. Ltd</general><scope>RBI</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200308</creationdate><title>COURSES OF SUBSTANCE USE AND SCHIZOPHRENIA IN THE DUAL-DIAGNOSIS PATIENTS: IS THERE A RELATIONSHIP?</title><author>S Goswami, G Singh, S K Mattoo, D Basu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b238t-299f33c861158b0bcb2ed3b4f09c67c5c0ecd96d03c44c9fd726ca6bba5d90c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age of Onset</topic><topic>Alcoholism - epidemiology</topic><topic>Behavior</topic><topic>Comorbidity</topic><topic>Diagnosis, Dual (Psychiatry)</topic><topic>Disease Progression</topic><topic>Dual diagnosis</topic><topic>Humans</topic><topic>India - epidemiology</topic><topic>Male</topic><topic>Marijuana Abuse - epidemiology</topic><topic>Middle Aged</topic><topic>Opioid-Related Disorders - epidemiology</topic><topic>Remission, Spontaneous</topic><topic>Retrospective Studies</topic><topic>Risk factors</topic><topic>Schizophrenia - diagnosis</topic><topic>Schizophrenia - epidemiology</topic><topic>Schizophrenia, Course, Dual-diagnosis</topic><topic>Schizophrenics</topic><topic>Socioeconomic Factors</topic><topic>Statistics</topic><topic>Substance abuse</topic><topic>Substance-Related Disorders - diagnosis</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Time Factors</topic><toplevel>online_resources</toplevel><creatorcontrib>S Goswami, G Singh, S K Mattoo, D Basu</creatorcontrib><collection>Bioline International</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Indian journal of medical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>S Goswami, G Singh, S K Mattoo, D Basu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>COURSES OF SUBSTANCE USE AND SCHIZOPHRENIA IN THE DUAL-DIAGNOSIS PATIENTS: IS THERE A RELATIONSHIP?</atitle><jtitle>Indian journal of medical sciences</jtitle><addtitle>Indian J Med Sci</addtitle><date>2003-08</date><risdate>2003</risdate><volume>57</volume><issue>8</issue><spage>338</spage><pages>338-</pages><issn>0019-5359</issn><abstract>Background: Interrelationship of schizophrenia and substance use is
complex and multifactorial. Examining the influence of various
psychoactive substances on course of patients with dual-diagnosis
schizophrenia may help to solve this riddle. Aim: To examine the
relationship of the courses of substance use and schizophrenic
symptomatology in substance abusing "dual-diagnosis" patients with
schizophrenia. Settings and Design: Outpatient Deaddiction and
Treatment Center of a tertiary care hospital with; retrospective
design. Methods and Material: Twenty-two substance abusing
dual-diagnosis patients with schizophrenia were investigated regarding
the course of substance use (abuse/dependence, use, non-use) and that
of schizophrenia (psychotic, non-psychotic, in remission). A graphical
representation of course of schizophrenia and substance abuse was made
and their relationship studied by superimposition of respective graphs.
Statistics : The Friedman two-way analysis of variance of ranks was
applied to see the relationship between time spent by patients while on
and off various substances. Results: In five cases, the onset of
schizophrenia preceded the onset of substance use. In seven out of 22
subjects, the schizophrenic exacerbation was clearly preceded by
increase in substance abuse in the preceding 2-12 months. In none of
the subjects decrease in substance use led to a decrease or increase in
schizophrenic symptoms. Conclusions: Although substance use disorder
preceded the onset of schizophrenic illness in the majority, and
increase in substance abuse preceded schizophrenic exacerbation in
one-third of dual-diagnosis patients, overall there was no evidence
that the course of substance use was associated with that of
schizophrenia after both disorders were diagnosed.</abstract><cop>India</cop><pub>Medknow Publications on behalf of Indian Journal of Medical Sciences Trust</pub><pmid>12944690</pmid></addata></record> |
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| ispartof | Indian journal of medical sciences, 2003-08, Vol.57 (8), p.338 |
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| recordid | cdi_gale_infotracgeneralonefile_A110115761 |
| source | MEDLINE; Bioline International; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adolescent Adult Age of Onset Alcoholism - epidemiology Behavior Comorbidity Diagnosis, Dual (Psychiatry) Disease Progression Dual diagnosis Humans India - epidemiology Male Marijuana Abuse - epidemiology Middle Aged Opioid-Related Disorders - epidemiology Remission, Spontaneous Retrospective Studies Risk factors Schizophrenia - diagnosis Schizophrenia - epidemiology Schizophrenia, Course, Dual-diagnosis Schizophrenics Socioeconomic Factors Statistics Substance abuse Substance-Related Disorders - diagnosis Substance-Related Disorders - epidemiology Time Factors |
| title | COURSES OF SUBSTANCE USE AND SCHIZOPHRENIA IN THE DUAL-DIAGNOSIS PATIENTS: IS THERE A RELATIONSHIP? |
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