Novel bipodal, tripodal, and tetrapodal 1,4-dihydropyridines — Microwave-assisted synthesis and structural confinements

The one pot, three component reaction of p-hydroxy benzaldehyde, β-ketoester, and ammonium acetate afforded the corresponding monopodal 1,4-dihydropyridines as building blocks, which in turn converted into diversified novel bipodal, tripodal, and tetrapodal 1,4-dihydropyridines with different alkyla...

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Veröffentlicht in:	Canadian journal of chemistry 2011-11, Vol.89 (10), p.1236-1244
Hauptverfasser:	Rajesh, Kancherla, Reddy, Bandapalli Palakshi, Vijayakumar, Vijayaparthasarathi
Format:	Artikel
Sprache:	eng
Schlagworte:	1,4-dihydropyridines bipodes Alkylation Ammonia Ammonium Ammonium acetate Benzaldehyde bipodal-tripodal-tetrapodal 1,4-dihydropyridines Chemical compounds Chemical reactions Chemical synthesis Hantzsch pyridines Hydroxybenzaldehydes irradiation microonde microwave irradiation NMR Nuclear magnetic resonance Pyridine pyridines de Hantzsch Structure tripodes ou tétrapodes
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container_title	Canadian journal of chemistry
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creator	Rajesh, Kancherla Reddy, Bandapalli Palakshi Vijayakumar, Vijayaparthasarathi
description	The one pot, three component reaction of p-hydroxy benzaldehyde, β-ketoester, and ammonium acetate afforded the corresponding monopodal 1,4-dihydropyridines as building blocks, which in turn converted into diversified novel bipodal, tripodal, and tetrapodal 1,4-dihydropyridines with different alkylating agents through conventional as well as microwave assisted reactions. The unambiguous structural confinements of the all the synthesized compounds were drawn out with the help of 2D NMR (H-H COSY and C-H COSY).
doi_str_mv	10.1139/v11-088
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subjects	1,4-dihydropyridines bipodes Alkylation Ammonia Ammonium Ammonium acetate Benzaldehyde bipodal-tripodal-tetrapodal 1,4-dihydropyridines Chemical compounds Chemical reactions Chemical synthesis Hantzsch pyridines Hydroxybenzaldehydes irradiation microonde microwave irradiation NMR Nuclear magnetic resonance Pyridine pyridines de Hantzsch Structure tripodes ou tétrapodes
title	Novel bipodal, tripodal, and tetrapodal 1,4-dihydropyridines — Microwave-assisted synthesis and structural confinements
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