ALT-946 and Aminoguanidine, Inhibitors of Advanced Glycation, Improve Severe Nephropathy in the Diabetic Transgenic (mREN-2)27 Rat

ALT-946 and Aminoguanidine, Inhibitors of Advanced Glycation, Improve Severe Nephropathy in the Diabetic Transgenic (mREN-2)27 Rat Jennifer L. Wilkinson-Berka 1 , Darren J. Kelly 2 , Suzanne M. Koerner 1 , Kassie Jaworski 1 , Belinda Davis 3 , Vicki Thallas 3 and Mark E. Cooper 3 1 Department of Phy...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2002-11, Vol.51 (11), p.3283-3289
Hauptverfasser:	WILKINSON-BERKA, Jennifer L, KELLY, Darren J, KOERNER, Suzanne M, JAWORSKI, Kassie, DAVIS, Belinda, THALLAS, Vicki, COOPER, Mark E
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - therapeutic use Aminoguanidine Animals Animals, Genetically Modified Associated diseases and complications Biological and medical sciences Blood Pressure Body Weight - drug effects Causes of Complications and side effects Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - complications Diabetes Mellitus, Experimental - physiopathology Diabetes. Impaired glucose tolerance Diabetic nephropathies Diabetic Nephropathies - drug therapy Diabetic Nephropathies - pathology Diabetic Nephropathies - physiopathology Diabetic nephropathy Endocrine pancreas. Apud cells (diseases) Endocrine system Endocrinopathies Enzyme Inhibitors - therapeutic use Glomerular Filtration Rate Glycation End Products, Advanced - metabolism Guanidines - therapeutic use Hemodynamics Hydrazines - therapeutic use Hypertension Immunohistochemistry Kidney Cortex - drug effects Kidney Cortex - pathology Medical sciences Metabolism Nitric oxide Nitric Oxide Synthase - antagonists & inhibitors Organ Size - drug effects Physiological aspects Protein metabolism Rats Rats, Mutant Strains
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