Enhancing the Activity of a Self-Inducible Promoter in IEscherichia coli/I through Saturation Mutation and High-Throughput Screening

The use of self-inducible promoters is a promising strategy to address metabolic imbalances caused by overexpression. However, the low activity of natural self-inducible promoters hinders their widespread application. To overcome this limitation, we selected the fic promoter as a model promoter to c...

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Veröffentlicht in:Fermentation (Basel) 2023-05, Vol.9 (5)
Hauptverfasser: Li, Jinyang, Tong, Sheng, Amin, Farrukh Raza, Khalid, Habiba, Chen, Kai, Zhao, Xiaoguang, Cai, Jinling, Li, Demao
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Sprache:eng
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