Synthesis of New Triazole-Based Thiosemicarbazone Derivatives as Anti-Alzheimer’s Disease Candidates: Evidence-Based In Vitro Study

Triazole-based thiosemicarbazone derivatives (6a–u) were synthesized then characterized by spectroscopic techniques, such as 1HNMR and 13CNMR and HRMS (ESI). Newly synthesized derivatives were screened in vitro for inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (Bu...

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Veröffentlicht in:	Molecules (Basel) 2022, Vol.28 (1)
Hauptverfasser:	Rahim, Fazal, Ullah, Hayat, Taha, Muhammad, Hussain, Rafaqat, Sarfraz, Maliha, Iqbal, Rashid, Iqbal, Naveed, Khan, Shoaib, Ali Shah, Syed Adnan, Albalawi, Marzough Aziz, Abdelaziz, Mahmoud A, Alatawi, Fatema Suliman, Alasmari, Abdulrahman, Sakran, Mohamed I, Zidan, Nahla, Jafri, Ibrahim, Khan, Khalid Mohammed
Format:	Report
Sprache:	eng
Schlagworte:	Alzheimer's disease Chemical properties Drug therapy Health aspects Organosulfur compounds Pharmaceutical research Production processes Triazoles
Online-Zugang:	Volltext
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