The Identification by Exome Sequencing of Candidate Genes in IBRCA/I-Negative Tunisian Patients at a High Risk of Hereditary Breast/Ovarian Cancer

(1) Background: Germline variants in BRCA1/BRCA2 genes explain about 20% of hereditary breast/ovarian cancer (HBOC) cases. In the present paper, we aim to identify genetic determinants in BRCA-negative families from the South of Tunisia. (2) Methods: Exome Sequencing (ES) was performed on the lympho...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Genes 2022, Vol.13 (8)
Hauptverfasser:	BenAyed-Guerfali, Dorra, Kifagi, Chamseddine, BenKridis-Rejeb, Wala, Ammous-Boukhris, Nihel, Ayedi, Wajdi, Khanfir, Afef, Daoud, Jamel, Mokdad-Gargouri, Raja
Format:	Report
Sprache:	eng
Schlagworte:	Analysis Breast cancer Exome sequencing Genes Genetic aspects Identification and classification Methods Ovarian cancer Risk factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!