Low-Molecular-Weight Mimetic of BDNF Loop 2 Reduces Ethanol Consumption in Female Rats

The study examined the effect of GTS-201, a low-molecular weight mimetic of brain-derived neurotrophic factor (BDNF) loop 2, on persistent alcohol craving in outbred male and female albino rats with ethanol preference score ~50% developed in the free choice paradigm between 10% ethanol and water ove...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2021-08, Vol.171 (4), p.441-444
Hauptverfasser:	Kolik, L. G., Nadorova, A. V., Grigorevskikh, E. M., Sazonova, N. M., Gudasheva, T. A., Durnev, A. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaldehyde Alcohol Alcohol Drinking - pathology Alcohol Drinking - prevention & control Alcohol, Denatured Alcoholism - drug therapy Alcoholism - pathology Animals Animals, Outbred Strains Biomedical and Life Sciences Biomedicine Biomimetic Materials - chemistry Biomimetic Materials - pharmacology Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - pharmacology Brain-Derived Neurotrophic Factor - therapeutic use Cell Biology Ethanol Ethanol - administration & dosage Female Internal Medicine Laboratory Medicine Male Molecular Weight Pathology Rats Rodents Sex Characteristics Sex differences
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