Quantitative Structure–Activity Relationship Analysis and Validation of New DNA Gyrase Inhibitors

Quantitative structure–activity relationship (QSAR) analysis was carried out for a series of 61 compounds with thiazole and benzthiazole moiety for inhibition of the DNA gyrase enzyme of Escherichia coli . The study was performed by conducting multiple linear regression analysis and followed by vali...

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Veröffentlicht in:	Pharmaceutical chemistry journal 2021-12, Vol.55 (9), p.886-907
Hauptverfasser:	Bhuvaneswari, S., Aakash, V. Bala, Ramalakshmi, N., Arunkumar, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis DNA Medicine Organic Chemistry Pharmacology/Toxicology Pharmacy
Online-Zugang:	Volltext
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