HLA polymorphisms and risk of glioblastoma in Koreans

Immune responses for cancer cells can be altered according to genetic variation of human leukocyte antigen (HLA). Association of HLA polymorphism with risk of various cancer types is well known. However, the association between HLA and glioblastoma (GBM) remains uncertain. We sought to evaluate the...

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Veröffentlicht in:	PloS one 2021-12, Vol.16 (12), p.e0260618-e0260618
Hauptverfasser:	Choi, Sang-Soo, Choi, Haeyoun, Baek, In-Cheol, Park, Soon A, Park, Jae-Sung, Kim, Tai-Gyu, Jeun, Sin-Soo, Ahn, Stephen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens Asians - genetics Autoimmune diseases Biology and Life Sciences Brain cancer Cancer Cancer therapies Case-Control Studies DNA methylation Drb1 protein Female Gene polymorphism Genetic Association Studies Genetic diversity Genotyping Genotyping Techniques Glioblastoma Glioblastoma - genetics Glioblastoma multiforme Glioma Haplotypes Health aspects Health risks Health sciences Histocompatibility antigen HLA Histocompatibility antigens HLA histocompatibility antigens HLA-A Antigens - genetics HLA-C Antigens - genetics HLA-DRB1 Chains - genetics Hospitals Humans Immune response Informed consent Leukocytes Male Males Medical prognosis Medical schools Medicine Medicine and Health Sciences Middle Aged Mutation Neurosurgery Pathogenesis Patients People and Places Polymerase chain reaction Polymorphism Polymorphism, Single Nucleotide Republic of Korea Risk Risk factors Statistical analysis Survival analysis Throat cancer Tissue typing Young Adult
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