A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Lei-gong-gen formula granule on a spontaneously hypertensive rat model

Background Lei-gong-gen formula granule (LFG) is a folk prescription derived from Zhuang nationality, the largest ethnic minority among 56 nationalities in China. It consists of three herbs, namely Eclipta prostrata (L.) L., Smilax glabra Roxb, and Centella asiatica (L.) Urb. It has been widely used...

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Veröffentlicht in:	Chinese medicine 2021-10, Vol.16 (1), p.1-99, Article 99
Hauptverfasser:	Li, Qiaofeng, Lan, Taijin, He, Songhua, Chen, Weiwei, Li, Xiaolan, Zhang, Weiquan, Liu, Ying, Zhang, Qiuping, Chen, Xin, Han, Yaoyao, Su, Zhiheng, Zhu, Dan, Guo, Hongwei
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Acids AKT protein Angiotensin II Antihypertensives Aorta Bioinformatics Blood pressure Body weight Centella asiatica (L.) Urb Chinese medicine Drug dosages Eclipta prostrata (L.) L Endothelial cells Endothelin 1 Heart beat Heart rate Histidine Hydrogen peroxide Hypertension Hypertrophy Integrative & Complementary Medicine Laboratory animals Life Sciences & Biomedicine Linalool Medical screening Medicine, Chinese Molecular biology mRNA Network pharmacology Niacin Nicotinic acid p-Hydroxybenzoic acid Peroxides Pharmaceuticals Pharmacology Pharmacology & Pharmacy Protein kinase Proteins Reagents Salicylic acid Science & Technology Shikimic acid Signal transduction Smilax glabra Roxb Thorax Vasodilation
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