Pharmacodynamic Effect of Ellagic Acid on Ameliorating Cerebral Ischemia/Reperfusion Injury

Cerebral ischemia/reperfusion (I/R) injury causes a larger population of disable patients and deaths annually. Three Tibetan prescriptions have been applied in alleviating the I/R injury for a 1,000 years. Interestingly, ellagic acid (EA) is one of the commonly dominated phytochemicals in these 3 pr...

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Veröffentlicht in:	Pharmacology 2019-11, Vol.104 (5-6), p.320-331
Hauptverfasser:	Wang, Yeye, Wu, Ying, Liang, Chen, Tan, Renxiang, Tan, Liwei, Tan, Rui
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - drug effects Brain - metabolism Brain - pathology Care and treatment Cell Survival - drug effects Cerebral ischemia Cytokines - immunology Development and progression Ellagic acid Ellagic Acid - pharmacology Ellagic Acid - therapeutic use Health aspects Infarction, Middle Cerebral Artery - drug therapy Infarction, Middle Cerebral Artery - metabolism Infarction, Middle Cerebral Artery - pathology Male Malondialdehyde - metabolism Oxidative Stress - drug effects PC12 Cells Pharmacology, Experimental Rats Rats, Sprague-Dawley Reperfusion injury Reperfusion Injury - drug therapy Reperfusion Injury - metabolism Reperfusion Injury - pathology Research Article Superoxide Dismutase - metabolism
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