The CBP KIX domain regulates long-term memory and circadian activity

Background: CREB-dependent transcription necessary for long-term memory is driven by interactions with CREB-binding protein (CBP), a multi-domain protein that binds numerous transcription factors potentially affecting expression of thousands of genes. Identifying specific domain functions for multi-...

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Veröffentlicht in:	BMC biology 2020-10, Vol.18 (1), p.155-155, Article 155
Hauptverfasser:	Chatterjee, Snehajyoti, Angelakos, Christopher C., Bahl, Ethan, Hawk, Joshua D., Gaine, Marie E., Poplawski, Shane G., Schneider-Anthony, Anne, Yadav, Manish, Porcari, Giulia S., Cassel, Jean-Christophe, Giese, K. Peter, Michaelson, Jacob J., Lyons, Lisa C., Boutillier, Anne-Laurence, Abel, Ted
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal behavior Animal memory Biological clocks Biology BMAL1 protein CBP KIX domain Circadian rhythm Circadian rhythms Cognitive ability Cognitive science CREB-binding protein Cyclic AMP response element-binding protein Fear conditioning Gene expression Genes Genetic aspects Hippocampus Kinases Life Sciences & Biomedicine Life Sciences & Biomedicine - Other Topics Long term memory Maze learning Memory Mutation Neuroscience Physiological aspects Proteins Rodents Science & Technology Short term memory Spatial memory Transcription activation Transcription factors Transcriptional coactivators
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