Increased Plasma Levels of Adenylate Cyclase 8 and cAMP Are Associated with Obesity and Type 2 Diabetes: Results from a Cross-Sectional Study

Adenylate cyclases (ADCYs) catalyze the conversion of ATP to cAMP, an important co-factor in energy homeostasis. Giving ADCYs role in obesity, diabetes and inflammation, we questioned whether calcium-stimulated ADCY isoforms may be variably detectable in human plasma. We report the results of a cros...

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Veröffentlicht in:	Biology (Basel, Switzerland) Switzerland), 2020-09, Vol.9 (9), p.244, Article 244
Hauptverfasser:	Abdel-Halim, Samy M., Al Madhoun, Ashraf, Nizam, Rasheeba, Melhem, Motasem, Cherian, Preethi, Al-Khairi, Irina, Haddad, Dania, Abu-Farha, Mohamed, Abubaker, Jehad, Bitar, Milad S., Al-Mulla, Fahd
Format:	Artikel
Sprache:	eng
Schlagworte:	ADCY1 ADCY3 ADCY8 Adenosine Adenylate cyclase adenylate cyclase 8 Age Biology Blood plasma Body mass index Calcium Cross-sectional studies Cyclic adenylic acid Cyclic AMP Diabetes Diabetes mellitus (non-insulin dependent) Energy balance Glucose Homeostasis Insulin resistance Isoforms Life Sciences & Biomedicine Life Sciences & Biomedicine - Other Topics Mutation Obesity Physiological aspects Plasma Plasma levels Proteins Risk factors Science & Technology Type 2 diabetes
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